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ProteomicsQuantitative proteomics analysis of Stra8-Pdcd5-/- mouse elongating spermatids
In order to investigate the molecular mechanism of PDCD5 in the regulation of spermatids development, elongating spermatids from Pdcd5F/F and Stra8-Pdcd5-/- mice were collected for quantitative proteomics analysis using TMT-based liquid chromatography-tandem mass spectrometry (LC-MS/MS) approach. A ...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-08 | PXD067835 | Pride
Pdcd5 Quantitative proteomics Tmt Mouse Elongating spermatids 
TranscriptomicsExpression data from shMiwi/shCaf1 transduced mouse elongating spermatids
We reasoned that the pi-RISC, by virtue of the enormous sequence portfolio of piRNAs, might mediate elimination of a large variety of mRNAs in late stages of spermiogenesis. Both Miwi-null and Caf1-null mice showed early spermiogenic arrest, preventing us from determining the role of MIWI and CAF1 i...
ORGANISM(S): Mus musculus 
2014-07-11 | E-GEOD-59291 | biostudies-arrayexpress
ProteomicsProteomics analysis of TRiC interactome from Stra8-Pdcd5-/- mouse elongating spermatids
In order to investigate the interaction proteins of TRiC in Stra8-Pdcd5-/- elongating spermatids, TRiC immunoprecipitation from Pdcd5F/F and Stra8-Pdcd5-/- elongating spermatids were collected for LC-MS/MS analysis. A total of 4419 proteins were quantified, and 375 proteins (p < 0.05, Foldchange > 1...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-08 | PXD067989 | Pride
Tric Proteomics Mouse Elongating spermatids 
ProteomicsThe late chromatoid body component TSSK2 associates with translational machinery in elongating spermatids in mice
Spermatogenesis culminates in a dramatic morphological transformation, including a tight compaction of the chromatin and nuclear re-shaping that largely silences transcription. Due to transcriptional silencing, the production of the sperm-specific proteins needed for the morphological transformation...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-27 | PXD065042 | Pride
Spermatogenesis Rnp granules Elongating spermatids Chromatoid body Tssk2 Male fertility Translation 
TranscriptomicsExpression data from shMiwi/shCaf1 transduced mouse elongating spermatids
We reasoned that the pi-RISC, by virtue of the enormous sequence portfolio of piRNAs, might mediate elimination of a large variety of mRNAs in late stages of spermiogenesis. Both Miwi-null and Caf1-null mice showed early spermiogenic arrest, preventing us from determining the role of MIWI and CAF1 i...
ORGANISM(S): Mus musculus 
2014-07-11 | GSE59291 | GEO
GenomicsGenome-wide occupancy of linker histone variant H1T2 in round/elongating spermatids of rats
Genome-wide occupancy of linker histone variant H1T2 in round/elongating spermatids of rats
PRJNA680756 | ENA
UnknownThe late chromatoid body component TSSK2 is involved in translational regulation in elongating spermatids in mice.
Not available
S-EPMC12529751 | biostudies-literature
Genomics
RNA sequencing data of PDCD5 in elongating spermatids
PRJNA1247127 | ENA
GenomicsMus musculus
Expression data from shMiwi/shCaf1 transduced mouse elongating spermatids
PRJNA254973 | ENA
OtherThe late chromatoid body component TSSK2 associates with translational machinery in elongating spermatids in mice
Spermatogenesis culminates in a dramatic morphological transformation, including a tight compaction of the chromatin and nuclear re-shaping that largely silences transcription. Due to transcriptional silencing, the production of the sperm-specific proteins needed for the morphological transformation...
ORGANISM(S): Mus musculus 
2025-12-02 | GSE262643 | GEO
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