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ProteomicsPARG regulates the proteosomal degradation of TARG1
ADP-ribosylation (ADPr) is a reversible modification of macromolecules critical for the regulation of genome stability, stress responses, and proteostasis. While the roles of ADPr transferases such as PARP1/2 and TNKS1/2 are well established, the cellular functions and regulatory mechanisms of ADPr ...
ORGANISM(S): Homo sapiens (Human) 
2026-01-02 | PXD065407 | Pride
Parp Ubiquitination Proteome Adp-ribosylation Proteasomal degradation Dna damage 
ProteomicsPARP1 auto-modification promotes faithful Okazaki fragment processing and limits replication fork speed
Poly(ADP-ribose) polymerase (PARP) inhibitors have proven their efficacy for treating tumors defective in homologous recombination via synthetic lethality. In response to DNA breaks, PARP1 is the primary ADP-ribosylation writer, modifying itself (auto-modification) and other proteins to facilitate r...
ORGANISM(S): Homo sapiens (Human) 
2025-10-02 | PXD066033 | Pride
Parp1 Ptm Okazaki fragment Adp-ribosylation Dna replication 
UnknownCharacterization of a culturable "Gastrospirillum hominis" (Helicobacter heilmannii) strain isolated from human gastric mucosa.
Not available
S-EPMC88651 | biostudies-literature
UnknownEfficacy of education outside the classroom to increase adolescent physical activity.
Not available
S-EPMC11568335 | biostudies-literature
UnknownEfficacy and mechanisms of an education outside the classroom intervention on pupils' health and education: the MOVEOUT study protocol.
Not available
S-EPMC10510120 | biostudies-literature
UnknownImpact of cell culture transition on adipose-derived mesenchymal stromal cells: Multi-omics analysis of small- vs large-scale production.
Not available
S-EPMC12270734 | biostudies-literature
UnknownA quantitative and site-specific atlas of the citrullinome reveals widespread existence of citrullination and insights into PADI4 substrates.
Not available
S-EPMC11189309 | biostudies-literature
UnknownPARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities.
Not available
S-EPMC10499325 | biostudies-literature
UnknownSetting a baseline for global urban virome surveillance in sewage.
Not available
S-EPMC7426863 | biostudies-literature
UnknownGenomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance.
Not available
S-EPMC9715550 | biostudies-literature
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