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ProteomicsProteomics of TurboID-induced biotinylated proteins from astrocyte and astrocyte endeet after acute peripheral inflammation
The brain vasculature is tightly regulated to control the exchange of substances between the periphery and the brain parenchyma at an interface called the blood-brain barrier (BBB). Astrocytes are glial cells that wrap the brain vasculature with a specialised structure called the endfoot, which is a...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-11 | PXD056232 | Pride
Mouse Brain Dia Ip Endfoot Isolation Astrocyte 
UnknownMolecular profiling of brain endothelial cell to astrocyte endfoot communication in mouse and human.
Not available
S-EPMC12592424 | biostudies-literature
UnknownTranscriptional network analysis of human astrocytic endfoot genes reveals region-specific associations with dementia status and tau pathology.
Not available
S-EPMC6098119 | biostudies-literature
UnknownAstrocyte endfoot formation controls the termination of oligodendrocyte precursor cell perivascular migration during development.
Not available
S-EPMC9922530 | biostudies-literature
UnknownCx43 carboxyl terminal domain determines AQP4 and Cx30 endfoot organization and blood brain barrier permeability.
Not available
S-EPMC8692511 | biostudies-literature
UnknownPurinergic signaling triggers endfoot high-amplitude Ca2+ signals and causes inversion of neurovascular coupling after subarachnoid hemorrhage.
Not available
S-EPMC5094310 | biostudies-literature
UnknownIncreased occurrence of pathological mitochondria in astrocytic perivascular endfoot processes and neurons of idiopathic intracranial hypertension.
Not available
S-EPMC7821105 | biostudies-literature
TranscriptomicsRiboTag RNA Sequencing Identifies Local Translation of HSP70 in Astrocyte Endfeet After Cerebral Ischemia
Brain ischemia causes disruption in cerebral blood flow and blood–brain barrier integrity, which are normally maintained by astrocyte endfeet. Emerging evidence points to dysregulation of the astrocyte translatome during ischemia, but its effects on the endfoot translatome are unknown. In this study...
ORGANISM(S): Mus musculus 
2025-01-27 | GSE286075 | GEO
TranscriptomicsLow testosterone promotes anxiety through astrocytic mitochondrial remodelling at the nucleus accumbens blood-brain barrier
Low testosterone is linked to anxiety in men, but its causal role and underlying brain mechanisms remain unknown. Here, using outbred male rats stratified by natural variation in anxiety-like behaviour, we establish its causal endocrine contribution and uncover an astrocytic mitochondrial mechanism ...
ORGANISM(S): Rattus norvegicus 
2026-09-07 | GSE346130 | GEO
UnknownA large portion of the astrocyte proteome is dedicated to perivascular endfeet, including critical components of the electron transport chain.
Not available
S-EPMC8504955 | biostudies-literature
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