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TranscriptomicsMicroarray-based transposon mapping analysis of Enterococcus faecium E1162 in a rat endocarditis model or control medium
Mapping of transposon mutant library during growth in Brain Heart Infusion (BHI) broth and in a rat endocarditis model. The goal of this study was to identify factors that play a role in E. faecium endocarditis by selection of transposon insertion mutants that lost the capacity to cause infections.
ORGANISM(S): Enterococcus faecium 
2016-03-24 | E-MTAB-4523 | biostudies-arrayexpress
ProteomicsIntegrated Plasma and Vegetation Proteomic Characterization of Infective Endocarditis for Early Diagnosis and Treatment
Infective endocarditis, a life-threatening condition, poses significant challenges for early diagnosis and personalized treatment due to insufficient biomarkers and limited understanding of its pathophysiology. Here, we analyzed plasma and vegetation proteomes from 238 patients with infective endoca...
ORGANISM(S): Homo Sapiens 
PXD062668 |
TranscriptomicsTranscription profiling of cardiac valves from patients with bacterial infectious endocarditis
Transcriptional profiles of cardiac valves from patients with bacterial infectious endocarditis (3 infected with Streptococcus sp. and 2 infected with Staphylococcus aureus) were compared with uninfected cardiac valves (7 patients) from patients with hemodynamic disturbing events
ORGANISM(S): Homo sapiens 
2009-10-23 | E-MEXP-1334 | biostudies-arrayexpress
TranscriptomicsGene Expression Analysis of Blood Reveals S100A11 and AQP9 as Potential Biomarkers of Infective Endocarditis
BackgroundM-bM-^@M-^TDiagnosis and pronostic assessment are challenging in infective endocarditis (IE). To investigate the host response during IE and identify potential biomarkers, we determined the circulating gene expression profile through a whole genome microarray analysis. Methods and ResultsM...
ORGANISM(S): Homo sapiens 
2012-03-12 | E-GEOD-29161 | biostudies-arrayexpress
ProteomicsProtein components of infective endocarditis vegetations and insights on their proteolysis using mass spectrometry-based N-terminomics
Infective endocarditis results in the growth of a vegetative mass on native or bio prosthetic valves hindering function and increasing risk of thromboses. This study set out to determine the proteomic composition of these vegetations including the influence of different micro-organisms and the prote...
ORGANISM(S): Homo sapiens (Human) 
2020-07-29 | PXD016415 | Pride
Staph a. Infective endocarditis Tails Ie 
ProteomicsProtein components of infective endocarditis vegetations and insights on their proteolysis using mass spectrometry-based N-terminomics
Infective endocarditis results in the growth of a vegetative mass on native or bio prosthetic valves hindering function and increasing risk of thromboses. This study set out to determine the proteomic composition of these vegetations including the influence of different micro-organisms and the prote...
ORGANISM(S): Homo sapiens (Human) 
2020-07-29 | PXD019129 | Pride
Degradomics Tails N-terminomics Infective endocarditis 
TranscriptomicsStaphylococcus aureus gene expression in a rat model of infective endocarditis
S. aureus has a propensity to cause endocarditis; diabetes mellitus is a frequent underlying comorbitity in patents with S. aureus endocarditis. S. aureus Affymetrix GeneChips were used to compare S. aureus expression properties in cardiac vegatations isolated from diabetic and nondiabetic rats. S. ...
ORGANISM(S): Staphylococcus aureus 
2014-11-01 | E-GEOD-62390 | biostudies-arrayexpress
GenomicsPandoraea pnomenusa possible endocarditis
Possible prosthetic valve endocarditis by Pandoraea pnomenusa and specific virulence mechanisms
PRJEB43050 | ENA
GenomicsStaphylococcus succinus: Infective Endocarditis in Human
Staphylococcus succinus: Infective Endocarditis in Human
PRJEB66420 | ENA
ProteomicsDataset in support of patients on clinical suspicion of infective endocarditis included in a study searching for novel putative biomarkers
Infective endocarditis (IE) has high mortality, partly due to delayed diagnosis and treatment. Currently, no biomarker can identify IE in patients with fever and clinical picture of infection. To find putative biomarkers we analyzed serum levels of two proteins found in cardiac valves, osteoproteger...
ORGANISM(S): Homo sapiens (Human) 
2020-02-26 | PXD010149 | Pride
Biomarkers  infective endocarditis  lfq lc-ms/ms  non-infective endocarditis  serum proteomics  2d-page 
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