Endolysins are peptidoglycan hydrolases produced at the end of the bacteriophage (phage) replication cycle to lyse the host cell. Gram-positive phages endolysins come in a variety of multi-modular forms that combine different catalytic domains and may have evolved to adapt to their bacterial hosts. ...
We report the different bactericidal ability of endolysin wild type and mutant and explain the pathway of lipopolysaccharide biosynthesis is the dominant factor.
