Endolysosomal protein

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Metabolite Name

Cholesterol-23,24,25,26,27-¹³C₅ (1)
Cholesterol (1)

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2025 (5)
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Transcription profiling by array (3)
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Lab affiliation

Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain. (2)
Department of Ophthalmology, LMU University Hospital, LMU Munich, Munich, Germany (2)
Ludwig-Maximilians-Universität München Genzentrum Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25 D-81377 München (2)
Scripps Research (2)
1- i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal 2- IBMC - Instituto de Biologia Celular e Molecular, Universidade do Porto, Portugal 3- ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Portugal (1)
Amicus Therapeutics (1)
Associate Professor of Neuroscience and BIO5 Institute University of Arizona (1)
Bioanalytical Chemistry Section, Department of Biology/Chemistry, Osnabrück University, Germany (1)
Bioanalytical Mass Spectrometry Group, Max Planck Institute for Multidisciplinary Sciences, 37077 Göttingen, Germany. (1)
Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom (1)
CNIC (1)
Calico Life Sciences (1)
Cambridge Institute for Medical Research, University of Cambridge (1)
Centre for Genomic Regulation (CRG), the Barcelona Institute For Science and Technology (BIST), Barcelona Biomedical Research Park (PRBB), Dr. Aiguader 88, 08003 Barcelona, Spain (1)
Chair of Biochemistry I, Biocenter, University of Wuerzburg (1)
Chiara Guerrera, IR1, HDR Head of the Proteomics Platform SFR Necker INSERM US24 Faculty of Medecine, University of Paris 160 rue de Vaugirard 75015 Paris Tél. : 01 40 61 54 67 (1)
Dana Farber Cancer Institute, Boston, MA Harvard Medical School, Boston, MA (1)
Department of Biochemistry and Molecular Biology, Infection and Immunity theme, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia (1)
Department of Cell Biology, Harvard Medical School, Boston MA (1)
Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. (1)
Department of Immunobiology, University of Lausanne (155 chemin des Boveresses 1066 Epalinges Switzerland) (1)
Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, The Netherlands (1)
Department of Neuroscience, Yale University School of Medicine (1)
Department of Pathology, University of California, San Francisco, USA (1)
Department of Pathology, University of Tennesee Health Science Center (1)
Department of Pharmaceutical Sciences Oregon State University College of Pharmacy Portland, OR 97301 USA (1)
Director of the UAB CCC Mass Spectrometry Shared Facility (1)
Drug Discovery Lab, Department of Neurology, University of California, Los Angeles, CA 90095, USA (1)
Drug Discovery and Evaluation Unit, Center for Research of Pathogenicity and Virulence of Parasites, BIOCEV, Charles University in Prague (1)
European Molecular Biology Laboratory (1)

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Compartmentalisation proteomics revealed endolysosomal protein network changes in goat model of atrial fibrillation

PRJNA949204 | ENA

Transmembrane protein 184B (TMEM184B) promotes endolysosomal acidification through vesicular proton pump regulation

Disruption of endolysosomal acidification is a hallmark of several neurodevelopmental and neurodegenerative disorders. Impaired acidification causes accumulation of toxic protein aggregates and disrupts neuronal homeostasis, yet the molecular mechanisms regulating endolysosomal pH in neurons remain ...

ORGANISM(S): Homo sapiens (Human)

2025-06-16 | PXD064977 | Pride

Compartmentalisation proteomics revealed endolysosomal protein network changes in a goat model of atrial fibrillation

The emerging roles of endolysosomes (EL) in AF have yet to be discovered, especially how the EL contribute to the development of AF within a slow time frame. To identify the EL role in AF, we applied proteomics, transcriptomics, integrated analysis, electron tomography, western blotting and enzyme a...

ORGANISM(S): Capra hircus x Ovis aries

2024-06-16 | PXD041056 | Pride

Endolysosomal protein Proteomics Atrial fibrillation Goat

Compartmentalisation proteomics revealed endolysosomal protein network changes in goat model of atrial fibrillation

To identify the role of the endolysosomal (EL) protein network in atrial fibrillation (AF), we applied a newly developed organelle isolation method to the AF goat model. To accomplish the goal, we used proteomics, transcriptomics, integrated analysis, enzyme assays, electron tomography, and western ...

ORGANISM(S): Capra hircus

2024-06-12 | GSE228289 | GEO

Endolysosomal protease leakage reprograms macrophage mitochondrial metabolism

Organelle crosstalk plays important functions in metabolic processes and is relevant to immunity, neurodegeneration, and cancer. The permeabilisation and rupture of endolysosomes during stress can induce inflammation and cell death. There is growing evidence that endomembrane damage does not always ...

ORGANISM(S): Homo sapiens (Human)

2022-10-30 | PXD026045 | Pride

Endolysosomal damage Organelle crosstalk Proteomics Mitochondrial metabolic reprogramming

Development and Comparative Evaluation of Endolysosomal Proximity Labeling-based Proteomic Methods in Human iPSC-derived Neurons

Proximity-based in situ labeling techniques offer a unique way to capture both stable and transient protein-protein and protein-organelle interactions. Combining this technology with mass spectrometry (MS)-based proteomics allows us to obtain snapshots of molecular microenvironments with nanometer r...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2020-10-10 | MSV000086260 | MassIVE

Assessing protein immunogenicity with a dendritic cell line-derived endolysosomal degradome.

Not available

S-EPMC3040223 | biostudies-literature

Mdm1/Snx13 is a novel ER-endolysosomal interorganelle tethering protein.

Not available

S-EPMC4539980 | biostudies-literature

α-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2.

Not available

S-EPMC4388928 | biostudies-literature

Tumor protein D52 controls trafficking of an apical endolysosomal secretory pathway in pancreatic acinar cells.