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TranscriptomicsMolecular Signature of Erythroblast Enucleation in Human Embryonic Stem Cells
While enucleation is a critical step in the terminal differentiation of human red blood cells, the molecular mechanisms underlying this unique process remain unclear. To investigate erythroblast enucleation, we studied the erythroid differentiation of human embryonic stem cells (hESCs), which provid...
ORGANISM(S): Homo sapiens 
2015-04-14 | E-GEOD-55532 | biostudies-arrayexpress
ProteomicsCDK9 interacts with a RanGTP-NEMP1-Importin-β complex to regulate erythroid enucleation
Erythroid enucleation is the final stage of erythroid terminal differentiation and involves the separation of an orthochromatic erythroblast into two daughter cells; a pyrenocyte containing the extruded nucleus, and a reticulocyte that will become a red blood cell. Our previous work identified CDK9 ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-01 | PXD072077 | Pride
Enucleation Cdk9 Erythropoiesis Importin-beta 
TranscriptomicsMolecular Signature of Erythroblast Enucleation in Human Embryonic Stem Cells
While enucleation is a critical step in the terminal differentiation of human red blood cells, the molecular mechanisms underlying this unique process remain unclear. To investigate erythroblast enucleation, we studied the erythroid differentiation of human embryonic stem cells (hESCs), which provid...
ORGANISM(S): synthetic construct 
2015-04-14 | E-GEOD-55530 | biostudies-arrayexpress
TranscriptomicsMolecular Signature of Erythroblast Enucleation in Human Embryonic Stem Cells
While enucleation is a critical step in the terminal differentiation of human red blood cells, the molecular mechanisms underlying this unique process remain unclear. To investigate erythroblast enucleation, we studied the erythroid differentiation of human embryonic stem cells (hESCs), which provid...
ORGANISM(S): Homo sapiens 
2015-04-14 | E-GEOD-55531 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse visual cortex from wild type animals sacrificed at P18 after mononuclear enucleation
Wild-type (C57Bl6) mice underwent monocular enucleation at P14 and were sacrificed 4 days later at P18. Bilateral (non-deprived and deprived) visual cortex was dissected from 1-mm thick coronal sections, and total RNA was extracted from the tissue lysate using Trizol (Gibco-BRL). Experiment Overall ...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-4263 | biostudies-arrayexpress
GenomicsMolecular Signature of Erythroblast Enucleation in Human Embryonic Stem Cells
Molecular Signature of Erythroblast Enucleation in Human Embryonic Stem Cells
PRJNA239885 | ENA
GenomicsMolecular Signature of Erythroblast Enucleation in Human Embryonic Stem Cells
While enucleation is a critical step in the terminal differentiation of human red blood cells, the molecular mechanisms underlying this unique process remain unclear. To investigate erythroblast enucleation, we studied the erythroid differentiation of human embryonic stem cells (hESCs), which provid...
ORGANISM(S): Homo sapiens Mus musculus Rattus norvegicus synthetic construct 
2015-04-14 | GSE55530 | GEO
TranscriptomicsMolecular Signature of Erythroblast Enucleation in Human Embryonic Stem Cells
While enucleation is a critical step in the terminal differentiation of human red blood cells, the molecular mechanisms underlying this unique process remain unclear. To investigate erythroblast enucleation, we studied the erythroid differentiation of human embryonic stem cells (hESCs), which provid...
ORGANISM(S): Mus musculus Homo sapiens Rattus norvegicus synthetic construct 
2015-04-14 | GSE55532 | GEO
TranscriptomicsMolecular Signature of Erythroblast Enucleation in Human Embryonic Stem Cells
While enucleation is a critical step in the terminal differentiation of human red blood cells, the molecular mechanisms underlying this unique process remain unclear. To investigate erythroblast enucleation, we studied the erythroid differentiation of human embryonic stem cells (hESCs), which provid...
ORGANISM(S): Homo sapiens 
2015-04-14 | GSE55531 | GEO
UnknownPreoperative predictors of enucleation time during en bloc 'no-touch' holmium laser enucleation of the prostate.
Not available
S-EPMC7661272 | biostudies-literature
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