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ProteomicsEndothelial EphB4 maintains vascular integrity and transport function in adult heart
Dilated cardiomyopathy is a frequently occurring human disease compromising heart function and a major cause of cardiac death. The causes of cardiomyopathies are often unknown. There is increasing evidence indicating that endothelial cells lining blood vessels control the homeostasis of various orga...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-20 | PXD012575 | Pride
Metabolism Mouse Heart Lc-msms Ephb4 Endothelium Gene expression 
TranscriptomicsRNA-seq of 12-weeks-old male murine heart ventricles.
RNA-Seq analysis of mouse cardiac transcriptome. RNA was isolated from the ventricles of 12-weeks-old male mice. Sequencing libraries were prepared using TrueSeq Stranded RNA LT Kit Ribo-Zero Gold (Illumina, 15032619). Libraries were pair-end sequenced on a MiSeq sequencer (Illumina) and mapped to t...
ORGANISM(S): Mus musculus 
2020-01-15 | E-MTAB-7686 | biostudies-arrayexpress
GenomicsIntestinal epithelial cell EphB4 deficiency on high fat diet-induced obesity
Intestinal epithelial cell EphB4 deficiency on high fat diet-induced obesity
PRJNA1189446 | ENA
GenomicsEffect of cancer cell knockdown of EphB4 in a Moc2 tumor model
Effect of cancer cell knockdown of EphB4 in a Moc2 tumor model
PRJNA828565 | ENA
GenomicsIdentification of Ephrin type-B receptor 4 (EphB4) as a critical mediator of tissue fibrosis [RNA-seq]
Identification of Ephrin type-B receptor 4 (EphB4) as a critical mediator of tissue fibrosis [RNA-seq]
PRJNA846712 | ENA
UnknownEphB4/EphrinB2 therapeutics in Rhabdomyosarcoma.
Not available
S-EPMC5560593 | biostudies-literature
TranscriptomicsEffect of cancer cell knockdown of EphB4 in a Moc2 tumor model
To investigate the functional significance of EphB4, we generated cancer cell-specific knockdown of EphB4 in a head and neck cancer cell line, Moc2, using shRNA approach. These cells along with the controls were orthotopically implanted in a C57BL/6 murine model and tumors for harvested for RNA-seq ...
ORGANISM(S): Mus musculus 
2022-04-28 | GSE201148 | GEO
GenomicsIdentification of Ephrin type-B receptor 4 (EphB4) as a critical mediator of tissue fibrosis [snRNA-seq]
Identification of Ephrin type-B receptor 4 (EphB4) as a critical mediator of tissue fibrosis [snRNA-seq]
PRJNA1141979 | ENA
TranscriptomicsIdentification of Ephrin type-B receptor 4 (EphB4) as a critical mediator of tissue fibrosis [RNA-seq]
Pulmonary fibrosis (PF) is a pathology associated with interstitial lung diseases (ILDs), including idiopathic pulmonary fibrosis (IPF). Fibrosis promotes continual secretion of extracellular matrix (ECM), producing non-functional scar tissue and causing organ failure. This study investigated the ty...
ORGANISM(S): Mus musculus 
2025-09-25 | GSE205612 | GEO
TranscriptomicsIdentification of Ephrin type-B receptor 4 (EphB4) as a critical mediator of tissue fibrosis [snRNA-seq]
Pulmonary fibrosis (PF) is a pathology associated with interstitial lung diseases (ILDs), including idiopathic pulmonary fibrosis (IPF). Fibrosis promotes continual secretion of extracellular matrix (ECM), producing non-functional scar tissue and causing organ failure. This study investigated the ty...
ORGANISM(S): Mus musculus 
2025-09-25 | GSE273467 | GEO
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