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MetabolomicsMetabolomic Analysis of Cauda Epididymal Fluid in Yaks and Cattle

The epididymis is the primary organ responsible for sperm maturation, with its caudal region serving as the primary storage site for mature sperm. The unique small molecule metabolites present in the cauda epididymal fluid not only facilitate the long-term storage of sperm but also ensure their s...

2025-09-29 | MTBLS13067 | MetaboLights
ProteomicsChronic inflammation drives epididymal tertiary lymphoid structure formation and autoimmune fertility disorders
We characterized the sperm proteins recognized by the antibodies in mouse serum and epididymal fluid after immune tolerance disruption by performing mass spectrometry-based label-free quantitative proteomics. For this, we immunoprecipitated sperm cell protein extractions with serum and epididymal fl...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-10 | PXD062944 | Pride
Autoanti-sperm antibodies Serum Treg depletion Immune tolerance Epididymal fluid 
ProteomicsChronic inflammation drives epididymal tertiary lymphoid structure formation and autoimmune fertility disorders
We characterized the sperm proteins recognized by the antibodies in mouse serum and epididymal fluid after immune tolerance disruption by performing mass spectrometry-based label-free quantitative proteomics. For this, we immunoprecipitated sperm cell protein extractions with serum and epididymal fl...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-10 | PXD058247 | Pride
Autoanti-sperm antibodies Serum Treg depletion Immune tolerance Epididymal fluid 
TranscriptomicsThe adult boar testicular and epididymal transcriptomes
Background - Mammalians gamete production takes place in the testis but when they exit this organ, although spermatozoa have a specialized and distinct morphology, they are immotile and infertile. It is only after their travel in the epididymis that sperm acquire their motility and fertility. Epidid...
ORGANISM(S): Sus scrofa 
2010-06-24 | E-GEOD-15614 | biostudies-arrayexpress
UnknownProteomics dataset of epididymal fluid, seminal plasma, and proteins loosely attached to epididymal and ejaculated sperm from Angus bulls.
Not available
S-EPMC9058950 | biostudies-literature
TranscriptomicsIsolation and next generation sequencing of epididymal extracellular vesicles reveals segmental patterns of miRNA expression and a potential mechanism for modification of the sperm epigenome.
Interest in the sperm epigenome continues to grow in view of the realization that it is vulnerable to dynamic modifications arising from a variety of paternal environment exposures and that this legacy can serve as an important determinant of intergenerational inheritance. It has been postulated tha...
ORGANISM(S): Mus musculus 
2016-08-25 | E-GEOD-79500 | biostudies-arrayexpress
UnknownMetabolomic Analysis of Cauda Epididymal Fluid in Yaks and Cattle.
Not available
S-EPMC12524237 | biostudies-literature
ProteomicsDisruption of immune tolerance changes epididymal extracellular vesicle (EV) protein cargo
We characterized the protein-content profile of epididymal EVs after disruption of immune tolerance by performing mass spectrometry-based label-free quantitative proteomics. EVs were obtained from the proximal and distal epididymides of WT and Foxp3- DTR (diphtheria toxin receptor) mice 2 weeks afte...
ORGANISM(S): Mus musculus (Mouse) 
2023-09-08 | PXD041223 | Pride
Treg depletion Epididymosomes Foxp3 Immune tolerance Extracellular vesicles 
UnknownSmooth muscle AKG/OXGR1 signaling regulates epididymal fluid acid-base balance and sperm maturation.
Not available
S-EPMC11749693 | biostudies-literature
UnknownProteome Profiling of Canine Epididymal Fluid: In Search of Protein Markers of Epididymal Sperm Motility.
Not available
S-EPMC10573609 | biostudies-literature
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