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ProteomicsAptamer-conjugated gold nanoparticles enable selective oligonucleotide delivery into muscle 2 stem cells to promote regeneration of dystrophic muscles
Inefficient targeting of muscle stem cells (MuSCs) represents a major bottleneck of current 27 therapeutic strategies for muscular dystrophies, as it precludes the possibility to promote 28 compensatory regeneration. Here we describe a novel delivery platform, based on gold nanoparticles, 29 that en...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-11 | PXD049295 | Pride
Gold nanoparticles Selex Proteomics Oligonucleotide Duchenne muscular dystrophy Aptamer 
TranscriptomicsMicroRNA profile in patients with multiple sclerosis versus healthy controls.
We tested the expression profile of 1146 miRNAs in PBMCs of 19 MS patients and 14 controls (discovery sample) and we explored their function either in vivo by performing a whole-genome mRNA profiling in same patients and in silico using bioinformatic prediction tool (miRbase software). These approac...
ORGANISM(S): Homo_sapiens 
2011-02-27 | E-MTAB-359 | biostudies-arrayexpress
TranscriptomicsmRNA profile in patients with multiple sclerosis versus healthy controls.
We tested the expression profile of 1146 miRNAs in PBMCs of 19 MS patients and 14 controls (discovery sample) and we explored their function either in vivo by performing a whole-genome mRNA profiling in same patients and in silico using bioinformatic prediction tool (miRbase software). These approac...
ORGANISM(S): Homo_sapiens 
2011-02-27 | E-MTAB-358 | biostudies-arrayexpress
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