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ProteomicsExtracellular vesicles from TGF-β-activated cancer-associated fibroblasts remodel the tumor microenvironment through EV surface-associated proteins
Cancer-associated fibroblasts (CAFs) are a major stromal cell type within the tumor microenvironment (TME). Transforming growth factor-β (TGF-β) is a key cytokine in the TME that activates CAFs, which alters their ability to remodel the extracellular matrix (ECM) and changes their secretome profile....
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD061656 | Pride
Cancer-associated fibroblast Tgf-β Tsg6 Cd8+ t cells Extracellular vesicles Ev surface-associated proteins 
ProteomicsMGAT3 and MGAT5 overexpression alters the protein cargo of extracellular vesicles released by metastatic melanoma cells
Extracellular vesicles (EVs) are potential non-invasive diagnostic, prognostic, and therapeutic tools. Additionally, they are important contributors to tumorigenesis. Glycosylation has been found to modulate the composition of the EV proteome, and increased amounts of beta 1,6-branched N-glycans, sy...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-11-08 | MSV000096340 | MassIVE
ProteomicsExtracellular Vesicles in COVID-19 convalescence can regulate T cell metabolism and function
Long-term T cell dysregulation has been reported following COVID-19 disease. Prolonged T cell activation is associated with initial disease severity and may be implicated mechanistically in the onset of long-covid symptoms. Here we assess the role of extracellular vesicles (EV) in regulating T cell ...
ORGANISM(S): Homo sapiens (Human) 
2023-06-28 | PXD043058 | Pride
Covid-19 Exosomes Extracellular vesicles 
ProteomicsIn-depth proteome profiling of small extracellular vesicles isolated from cancer cell lines and patient serum
Extracellular Vesicle (EV) secretion has been observed from most types of normal and tumor cells. These EVs contain a variety of distinctive cargo where tumor-derived serum proteins in EVs secreted into the bloodstream can be used to provide a minimally invasive method for clinical monitoring. We ha...
ORGANISM(S): Homo Sapiens (human) 
2024-09-08 | PXD045198 | JPOST Repository
UnknownCharacterization of large extracellular vesicles (L-EV) derived from human regulatory macrophages (Mreg): novel mediators in wound healing and angiogenesis?
Not available
S-EPMC9887800 | biostudies-literature
UnknownExtracellular Histones as Exosome Membrane Proteins Regulated by Cell Stress.
Not available
S-EPMC11840699 | biostudies-literature
ProteomicsAltered Extracellular Vesicle-derived protein and microRNA signatures in bronchoalveolar lavage fluid from COPD patients
Abstract: Chronic obstructive pulmonary disease (COPD) is a progressive lung disease for which there is no cure. Accumulating research results suggest a role for extracellular vesicles (EVs) in the pathogenesis of COPD. This study aimed to uncover the involvement of EVs and their molecular cargo in ...
ORGANISM(S): Homo sapiens (Human) 
2024-06-23 | PXD049998 | Pride
Copd Bronchoalveolar lavage Proteomics Inflammation Extracellular vesicles Mirna 
TranscriptomicsCharacterization and Small RNA Content of Extracellular Vesicles in Follicular Fluid of Developing Bovine Antral Follicles
Exosomes and microvesicles (i.e., extracellular vesicles; EVs) have been identified within ovarian follicular fluid, and recent evidence suggests that EVs are able to elicit profound effects on ovarian cell function. While existence of miRNA within EVs has been reported, it remains unknown if EV si...
ORGANISM(S): Bos taurus 
2016-02-09 | E-GEOD-74879 | biostudies-arrayexpress
ProteomicsProteome of Verticillium dahliae extracellular vesicles and mycelia
To identify EV-associated V. dahliae proteins, we conducted a comparative proteomic analysis of isolated EVs and total mycelial proteins. Total mycelial proteins served as the control to identify proteins specifically enriched in ultracentrifugation-purified EVs. This analysis identified two previou...
ORGANISM(S): Verticillium Dahliae 
PXD067443 |
ProteomicsProteome of Verticillium dahliae extracellular vesicles
To identify EV-associated V. dahliae proteins, we conducted a comparative proteomic analysis of isolated EVs and total mycelial proteins. Total mycelial proteins served as the control to identify proteins specifically enriched in ultracentrifugation-purified EVs. This analysis identified two previou...
ORGANISM(S): Verticillium Dahliae 
2025-12-24 | PXD072388 |
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