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UnknownTSG6 affects anti cancer drug resistance and angiogenesis in 3D spheroid model of canine mammary gland tumor cells.
Not available
S-EPMC12373961 | biostudies-literature
UnknownCD317 stabilizes TNFR1 and confers the anti-inflammatory functions of MSCs via NF-κB/TSG6 pathway.
Not available
S-EPMC12282008 | biostudies-literature
UnknownGlucocorticoid activates STAT3 and NF-κB synergistically with inflammatory cytokines to enhance the anti-inflammatory factor TSG6 expression in mesenchymal stem/stromal cells.
Not available
S-EPMC10796730 | biostudies-literature
UnknownHuman Synovial Mesenchymal Stem Cells Expressed Immunoregulatory Factors IDO and TSG6 in a Context of Arthritis Mediated by Alphaviruses.
Not available
S-EPMC10649115 | biostudies-literature
UnknownDynamic compaction of human mesenchymal stem/precursor cells into spheres self-activates caspase-dependent IL1 signaling to enhance secretion of modulators of inflammation and immunity (PGE2, TSG6, and STC1).
Not available
S-EPMC3834191 | biostudies-literature
UnknownImproved therapeutic consistency and efficacy of CD317<sup>+</sup> MSCs through stabilizing TSG6 by PTX3.
Not available
S-EPMC10976765 | biostudies-literature
TranscriptomicsTNFα-stimulated gene 6 (TSG-6) is a key molecule for stemness and a predictive marker for biological properties of mesenchymal stem cells
The major aim is to decipher the functional biological activity of TSG6 by transcriptional profiling on mouse Mesenchymal stem cells in the presence and abesence of TSG6. Here, we investigate, by approaching with functional validations of the data set generated by RNA-sequencing data, how the lack o...
ORGANISM(S): Mus musculus 
2019-04-21 | GSE109114 | GEO
UnknownTSG6 promotes epithelial-mesenchymal transition and tumor-associated macrophage polarization through Smad2/3 and MAPK signaling by facilitating TSG6-CD44-TGFβR1 or EGFR complex formation
Not available
S-EPMC12374808 | biostudies-literature
ProteomicsExtracellular vesicles from TGF-β-activated cancer-associated fibroblasts remodel the tumor microenvironment through EV surface-associated proteins
Cancer-associated fibroblasts (CAFs) are a major stromal cell type within the tumor microenvironment (TME). Transforming growth factor-β (TGF-β) is a key cytokine in the TME that activates CAFs, which alters their ability to remodel the extracellular matrix (ECM) and changes their secretome profile....
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD061656 | Pride
Cancer-associated fibroblast Tgf-β Tsg6 Cd8+ t cells Extracellular vesicles Ev surface-associated proteins 
TranscriptomicsExpression data of organoid derived from HSCs
To investigate the differences in mRNA expression profiles between TSG-6 or vehicle treated Hu-pHSCs and BM-MSCs organoid spheroids, we performed mRNA microarrays for total RNA extracts isolated from these spheroids (vehicle: CON/3D=3, TSG6: TSG-6/3D=4, BM: BM-MSCs3D=3) We used microarrays to detail...
ORGANISM(S): Homo sapiens 
2021-10-16 | GSE121298 | GEO
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