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TranscriptomicsTranscription profiling of human umbilical vein endothelial cells (HUVEC) treated with thrombin and leukotriene D4 (LTD4) with ethanol controls to delinate Cysteinyl leukotrienes mode of action
Cysteinyl leukotrienes (cysLT), i.e. LTC4, LTD4, and LTE4, are lipid mediators derived from the 5-lipoxygenase pathway. The cysLT receptors cysLT1-R and cysLT2-R are expressed on different target cells and mediate inflammatory reactions in tissue- and LT-R-specific ways. Though endothelial cells (EC...
ORGANISM(S): Homo sapiens 
2007-10-27 | E-GEOD-3589 | biostudies-arrayexpress
TranscriptomicsCryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling
This study was designed to provide additional insight into testicular hormone production and responsiveness in the orl strain and complement ongoing efforts to characterize the genetic basis of cryptorchidism in this isolated rat colony. Gubernacula were harvested from Long Evans and ORL rat embryos...
ORGANISM(S): Rattus norvegicus 
2014-07-02 | E-GEOD-57924 | biostudies-arrayexpress
ProteomicsSecretome from TXNIP knockout human colorectal cell line (DLD1)
Chemotherapy, the standard of care treatment for cancer patients with advanced disease, has been increasingly recognised to activate host immune responses to produce durable outcomes. Here, in colorectal adenocarcinoma (CRC) we identify oxaliplatin-induced Thioredoxin Interacting Protein (TXNIP), a ...
ORGANISM(S): Homo sapiens (Human) 
2024-08-12 | PXD051666 | Pride
Human Txnip Colorectal Secreted 
UnknownImpact of a Powdered Meal Replacement on Metabolism and Gut Microbiota (PREMIUM) in individuals with excessive body weight: a study protocol for a randomised controlled trial.
Not available
S-EPMC11148686 | biostudies-literature
TranscriptomicsTranscription profiling of mouse fetal heart from wild type and Estrogen-related Receptor gamma (ERRg) knockout strains
3 ventricles from E18.5 male mice were pooled for each array. Three arrays per genotype. Title: ERRγ Directs and Maintains the Transition to Oxidative Metabolism in the Post-Natal Heart; Abstract: At birth the heart undergoes a critical metabolic switch to transition from a predominant dependence o...
ORGANISM(S): Mus musculus 
2009-04-30 | E-GEOD-8199 | biostudies-arrayexpress
UnknownOrigin of Free Energy Barriers of Decarboxylation and the Reverse Process of CO2 Capture in Dimethylformamide and in Water.
Not available
S-EPMC8058934 | biostudies-literature
UnknownHypertonic sodium lactate improves microcirculation, cardiac function, and inflammation in a rat model of sepsis.
Not available
S-EPMC7298868 | biostudies-literature
UnknownPhase III Randomized Study of 4 Weeks of High-Dose Interferon-α-2b in Stage T2bNO, T3a-bNO, T4a-bNO, and T1-4N1a-2a (microscopic) Melanoma: A Trial of the Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Cancer Research Group (E1697).
Not available
S-EPMC5455684 | biostudies-literature
UnknownImproving Communication in Nursing Homes Using Plan-Do-Study-Act Cycles of an SBAR Training Program.
Not available
S-EPMC9981342 | biostudies-literature
TranscriptomicsCircadian patterns of gene expression in the human brain and disruption in major depressive disorder
A cardinal symptom of Major Depressive Disorder (MDD) is the disruption of circadian patterns. Yet, to date, there is no direct evidence of circadian clock dysregulation in the brains of MDD patients. Circadian rhythmicity of gene expression has been observed in animals and peripheral human tissues,...
ORGANISM(S): Homo sapiens 
2013-04-20 | E-GEOD-45642 | biostudies-arrayexpress
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