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MetabolomicsLipopolysaccharides from Ralstonia solanacearum induce a broad metabolomic response in Solanum lycopersicum

Ralstonia solanacearum, one of the most destructive crop pathogens worldwide, causes bacterial wilt disease in a wide range of host plants. The major component of the outer membrane of Gram-negative bacteria, lipopolysaccharides (LPS), has been shown to function as elicitors of plant defense lead...

2023-08-08 | MTBLS7324 | MetaboLights
UnknownMeta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways.
Not available
S-EPMC4603338 | biostudies-literature
MetabolomicsUntargeted plasma metabolome identifies biomarkers in patients with extracranial arteriovenous malformations

OBJECTIVE: This study aimed to investigate the plasma metabolic profile of patients with extracranial arteriovenous malformations (AVM).

METHOD: Plasma samples were collected from 32 AVM patients and 30 healthy controls (HC). Ultra-high performance liquid c...

2023-10-30 | MTBLS7753 | MetaboLights
MetabolomicsSerum metabolomic profiles for distinguishing lung cancer from pulmonary tuberculosis: identification of rapid and noninvasive biomarker

BACKGROUND: Pulmonary tuberculosis (TB) and lung cancer (LC) have similar clinical symptoms and atypical imaging findings which are easily misdiagnosed. There is an urgent need for a noninvasive, rapid and accurate biomarker for distinguishing LC from TB.

METHODS:

2024-01-16 | MTBLS6990 | MetaboLights
MetabolomicsHuman Archaeological Dentin as Source of Polar and Less Polar Metabolites for Untargeted Metabolomic Research: The Case of Yersinia pestis
Metabolomic approaches, such as in clinical applications of living individuals, have shown potential use for solving questions regarding the past when applied to archaeological material. Here, we study for the first time the potential of this Omic approach as applied to metabolites extracted from ar...
2024-03-15 | MTBLS7394 | MetaboLights
UnknownVisible neural networks for multi-omics integration: a critical review.
Not available
S-EPMC12310660 | biostudies-literature
UnknownProfiling the Atopic Dermatitis Epidermal Transcriptome by Tape Stripping and BRB-seq.
Not available
S-EPMC9181476 | biostudies-literature
ProteomicsSpatially-targeted optical microproteomics timecourse of rat myocardial infarction
Myocardial infarction (MI) results from occlusion of blood supply to the heart muscle causing death of cardiac muscle cells. Following myocardial infarction (MI), scar formation acts to mechanically stabilise the injured heart to prevent rupture and death. While fibroblasts and macrophages are impli...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-10-31 | PXD034413 | Pride
Cardiac Heart Macrophage Cd68 Rat Sma Microproteomics Fibroblast Myocardial infarction 
ProteomicsDifferential regulation of extracellular matrix proteins in three recurrent liver metastases of a single patient with colorectal cancer
Colorectal cancer (CRC) patients suffer from the second highest mortality among all cancer entities. In half of all CRC patients, colorectal cancer liver metastases (CRLM) can be observed. Metastatic colorectal cancer is associated with poor overall survival and limited treatment options. Even after...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD020109 | Pride
Ecm Prognostic factor Colorectal liver metastasis Crlm Proteomics Colorectal cancer Ecm signatures Metachronous liver metastasis Crc Extracellular matrix Lc-ms/ms 
UnknownCell Painting for cytotoxicity and mode-of-action analysis in primary human hepatocytes.
Not available
S-EPMC11785178 | biostudies-literature
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