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ProteomicsTemporally & Spatially-Resolved Microproteomics and MALDI MSI Lipidomic Analysis for Traumatic Brain Injury
Using an experimental TBI rat model of mild/moderate Controlled Cortical Impact (CCI) injury, we combined large-scale proteomics identification and relative quantification using Spatially-Resolved Microproteomics with MALDI MS Imaging of Lipids. Spatially by studying ...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-06-19 | PXD011262 | Pride
Spatiotemporal microproteomics Macrophage Traumatic brain injury Long-chain acylcarnitine Astrocyte Substantia nigra 
ProteomicsEvaluation of Non-Supervised MALDI Mass Spectrometry Imaging Combined to MicroProteomics for Glioma Grade III Classification
An integrated diagnosis using molecular features is recommended in the updated World Health Organization (WHO) classification. Our aim was to explore the role of MALDI-Mass spectrometry imaging (MSI) coupled to microproteomics in order to classify anaplastic glioma by integration of clinical data.
ORGANISM(S): Homo sapiens (Human) 
2016-12-13 | PXD004437 | Pride
Matrix-assisted laser desorption/ionization mass spectrometry imaging Anaplastic glioma Microproteomics 
UnknownMapping Spatiotemporal Microproteomics Landscape in Experimental Model of Traumatic Brain Injury Unveils a link to Parkinson's Disease.
Not available
S-EPMC6683007 | biostudies-literature
UnknownLaser microdissection-based microproteomics of the hippocampus of a rat epilepsy model reveals regional differences in protein abundances.
Not available
S-EPMC7064578 | biostudies-literature
ProteomicsMicroproteomics application for the limited number of cells
Mass spectrometry (MS)-based proteomics explores in-depth proteome, however, the analysis of cell subsets, which might be minor population, is hampered due to a multistep procedure for sample preparation and purification. Along those lines, optimization of proteomics workflow toward limited number...
ORGANISM(S): Homo Sapiens (human) 
2017-07-18 | PXD005096 | JPOST Repository
UnknownAutomated Spatially Targeted Optical Microproteomics Investigates Inflammatory Lesions In Situ.
Not available
S-EPMC8969901 | biostudies-literature
UnknownDetermining composition of micron-scale protein deposits in neurodegenerative disease by spatially targeted optical microproteomics.
Not available
S-EPMC4630677 | biostudies-literature
UnknownAutomated Spatially Targeted Optical Microproteomics (autoSTOMP) to Determine Protein Complexity of Subcellular Structures.
Not available
S-EPMC8454273 | biostudies-literature
ProteomicsDetermining composition of micron-scale protein deposits in neurodegenerative disease by spatially targeted optical microproteomics
Spatially targeted optical microproteomics (STOMP) is a novel proteomics technique for interrogating micron-scale regions of interest (ROI) in mammalian tissue, with no requirement for genetic manipulation. Methanol or formalin fixed specimens are stained with fluorescent dyes or antibodies to visua...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2015-11-18 | PXD002959 | Pride
Neurodegenerative disease 
UnknownCombined Mass Spectrometry Imaging and Top-down Microproteomics Reveals Evidence of a Hidden Proteome in Ovarian Cancer.
Not available
S-EPMC5514399 | biostudies-literature
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