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ProteomicsTnfaip2/Exoc3 controls exit from pluripotency by mediating lipid droplet formation and FA-induced differentiation
The decline in stem cell function leads to impairments in tissue homeostasis but genetic factors that control differentiation and de-differentiation of stem cells in the context of tissue homeostasis remain to be delineated. Here we show that Tnfaip2 (a target gene of TNFa/NFkB signaling) has an ess...
ORGANISM(S): Mus musculus (Mouse) 
2020-11-18 | PXD014628 | Pride
Neoblast Exoc3 Induced pluripotent stem cells Vim Lipid metabolism and fatty acids Tnfaip2 Differentiation Embryonic stem cells Homeostasis 
UnknownTnfaip2/exoc3-driven lipid metabolism is essential for stem cell differentiation and organ homeostasis.
Not available
S-EPMC7788457 | biostudies-literature
GenomicsTnfaip2/Exoc3 driven lipid metabolism is essential for stem cell differentiation & organ homeostasis [Schmidtea mediterranea]
Tnfaip2/Exoc3 driven lipid metabolism is essential for stem cell differentiation & organ homeostasis [Schmidtea mediterranea]
PRJNA554667 | ENA
GenomicsTnfaip2/Exoc3 driven lipid metabolism is essential for stem cell differentiation & organ homeostasis [Mus musculus, 1]
Tnfaip2/Exoc3 driven lipid metabolism is essential for stem cell differentiation & organ homeostasis [Mus musculus, 1]
PRJNA554668 | ENA
GenomicsTnfaip2/Exoc3 driven lipid metabolism is essential for stem cell differentiation & organ homeostasis [Mus musculus, 2]
Tnfaip2/Exoc3 driven lipid metabolism is essential for stem cell differentiation & organ homeostasis [Mus musculus, 2]
PRJNA625650 | ENA
UnknownLoss of the exocyst complex component EXOC3 promotes hemostasis and accelerates arterial thrombosis.
Not available
S-EPMC7876885 | biostudies-literature
TranscriptomicsTnfaip2/Exoc3 driven lipid metabolism is essential for stem cell differentiation & organ homeostasis [Schmidtea mediterranea]
Lipid metabolism is recognized as a key process for stem cell maintenance and differentiation but genetic factors that instruct stem cell function by influencing lipid metabolism remain to be delineated. Here we identify Tnfaip2 as an inhibitor of reprogramming of mouse fibroblasts into induced plur...
ORGANISM(S): Schmidtea mediterranea 
2020-11-16 | GSE134300 | GEO
TranscriptomicsTnfaip2/Exoc3 driven lipid metabolism is essential for stem cell differentiation & organ homeostasis [Mus musculus, 2]
Lipid metabolism is recognized as a key process for stem cell maintenance and differentiation but genetic factors that instruct stem cell function by influencing lipid metabolism remain to be delineated. Here we identify Tnfaip2 as an inhibitor of reprogramming of mouse fibroblasts into induced plur...
ORGANISM(S): Mus musculus 
2020-11-16 | GSE148758 | GEO
TranscriptomicsTnfaip2/Exoc3 driven lipid metabolism is essential for stem cell differentiation & organ homeostasis [Mus musculus, 1]
Lipid metabolism is recognized as a key process for stem cell maintenance and differentiation but genetic factors that instruct stem cell function by influencing lipid metabolism remain to be delineated. Here we identify Tnfaip2 as an inhibitor of reprogramming of mouse fibroblasts into induced plur...
ORGANISM(S): Mus musculus 
2020-11-16 | GSE134301 | GEO
UnknownDeletion of Exoc7, but not Exoc3, in male germ cells causes severe spermatogenesis failure with spermatocyte aggregation in mice.
Not available
S-EPMC11254494 | biostudies-literature
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