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Extracellular vesicles (EVs) are membrane-enclosed nanoparticles containing specific repertoires of genetic material. In mammals, EVs can mediate the horizontal transfer of various cargos and signaling molecules, notably miRNA and mRNA species. Whether this form of intercellular communication prevai...
ORGANISM(S): Homo sapiens 
In this study, we show for the first time that the tick Haemaphysalis longicornis secretes EVs in saliva that resembles exosomes. EVs were purified from pilocarpine induced saliva of partially engorged H. longicornis ticks. Electron microscopy analysis revealed the presence of exosome-like vesicles ...
ORGANISM(S): Haemaphysalis Longicornis 
2020-07-10 | PXD020300 |
Secreted extracellular vesicles play an important role in pathogen-host interactions. Increased knowledge of schistosome extracellular vesicles could provide insights into schistosome-host interactions and enable the development of novel intervention strategies to inhibit parasitic processes and les...
ORGANISM(S): Schistosoma japonicum (Blood fluke) 
2018-10-27 | PXD003364 | Pride
Extracellular vesicles (EVs) have been characterized from many species of parasitic helminths, and recent experimental evidence supports important functions for their cargo in host-parasite relationships. Here, we carried out a detailed proteomic analysis of two populations of EVs – exosome like ves...
ORGANISM(S): Schistosoma mansoni (Blood fluke) 
2019-10-17 | PXD015857 | Pride
We have analyzed six different extracelular vesicles isolation protocols from plasma of patients coinfected with human immunodeficiency virus and hepatitis C virus (HIV/HCV). In addition, two different RNA isolation kit were used for each protocol, one phenol-based and another pehenol-free kit. Same...
ORGANISM(S): Homo sapiens 
Extracellular vesicles (EVs) have been characterized from many species of parasitic helminths, and recent experimental evidence supports important functions for their cargo in host-parasite relationships. Here, we carried out the first proteomic analysis of two populations of EVs – exosome like vesi...
ORGANISM(S): Schistosoma haematobium 
2020-06-26 | PXD019462 | Pride
Genomics
MicroRNA of algal exosome-like vesicles
Examining the role of exosomes in the life cycle of CrPV in Drosophila Melanogaster. sing prquantitative proteomics we find CrPV proteins in exosome-like vesicles, which upon further aanalysis appear to facilitate infection.
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2018-11-14 | PXD011271 | Pride
Scope: Adipose tissue is regarded as a true endocrine organ. Recent studies showed that adipose tissue derived exosomes could serve as carrier of circulating miRNAs to regulate distant targets. However, the characteristics of exosomal proteins released from adipose tissue have not been investigated ...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-07-02 | PXD013270 | Pride
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