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TranscriptomicsTranscription profiling of hip1::ura4+ and slm9::ura4+ S. pombe to investigate the role of the HIRA histone chaperone complex
The assembly of nucleosomes by histone chaperones is an important component of transcriptional regulation. Here we have assessed the global roles of the S. pombe HIRA histone chaperone complex. Microarray analysis indicates that inactivation of the HIRA complex results in increased expression of at ...
ORGANISM(S): Schizosaccharomyces pombe 
2009-07-22 | E-MTAB-130 | biostudies-arrayexpress
UnknownThe Molecular Chaperone Heat Shock Protein 70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA Damage and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Signaling Pathways.
Not available
S-EPMC6469921 | biostudies-literature
ProteomicsExpanding the Family of Extracellular Chaperones: Identification of Plasma Proteins with Chaperone Activity
Proteostasis, the balance of protein synthesis, folding and degradation, is essential to maintain cellular function and viability, and the many known intracellular chaperones are recognised as playing key roles in sustaining life. In contrast, the identity of constitutively secreted extracellular ch...
ORGANISM(S): Homo sapiens (Human) 
2021-09-24 | PXD027042 | Pride
Proteostasis Plasminogen activator inhibitor 3 Extracellular chaperones C1s C1r Vitronectin Prothrombin 
UnknownDnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins.
Not available
S-EPMC4946142 | biostudies-literature
UnknownDNAJB6-Containing Extracellular Vesicles as Chaperone Delivery Systems: A Proteomic Analysis.
Not available
S-EPMC9698516 | biostudies-literature
UnknownExtracellular and Non-Chaperone Function of Heat Shock Protein-90α Is Required for Skin Wound Healing.
Not available
S-EPMC6559362 | biostudies-literature
UnknownThe extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model.
Not available
S-EPMC8357826 | biostudies-literature
ProteomicsExtracellular vesicles from pancreatic cancer cells activate mast cells which in turn promote tumor cell proliferation and establish a tumor-supportive microenvironment
Background and aim: Recent studies reveal a critical role of tumor cell-released extracellular vesicles (EVs) in pancreatic cancer progression. Driver genes directing EV function, the EV-recipient cells, as well as their cellular response to EV uptake remain, however, to be identified. To address th...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-12-06 | MSV000093583 | MassIVE
UnknownComputational Analysis of the Interactions between the S100B Extracellular Chaperone and Its Amyloid β Peptide Client.
Not available
S-EPMC8037576 | biostudies-literature
UnknownExpanding the family of extracellular chaperones: Identification of human plasma proteins with chaperone activity.
Not available
S-EPMC8521303 | biostudies-literature
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