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Genomics
C1R and C1R-B*57:01 RNA-Seq
PRJNA453631 | ENA
ProteomicsDIA acquisition of the immunopeptidomes of C1R-B*57:01 and C1R-A*02:01 cell lines
Immunopeptidomes are the peptide repertoires bound by the molecules encoded by the major histocompatibility complex (MHC) (human leukocyte antigen (HLA) in humans). These HLA-peptide complexes are presented on the cell surface for immune T cell recognition. Immunopeptidomics utilizes tandem mass spe...
ORGANISM(S): Homo sapiens (Human) 
2023-02-13 | PXD034539 | Pride
Mass spectrometry  immunopeptidomics  dia  software tools benchmark  hla-bound peptides  spectral library 
ProteomicsDDA acquisition of the immunopeptidomes of C1R-B*57:01 and C1R-A*02:01 cell lines
Immunopeptidomes are the peptide repertoires bound by the molecules encoded by the major histocompatibility complex (MHC) (human leukocyte antigen (HLA) in humans). These HLA-peptide complexes are presented on the cell surface for immune T cell recognition. Immunopeptidomics utilizes tandem mass spe...
ORGANISM(S): Homo sapiens (Human) 
2023-02-13 | PXD034429 | Pride
Mass spectrometry  immunopeptidomics  hla-bound peptides  dda  spectral library 
UnknownA novel human complement-related protein, C1r-like protease (C1r-LP), specifically cleaves pro-C1s.
Not available
S-EPMC1134944 | biostudies-literature
GenomicsmRNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1r.
mRNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1r.
PRJNA730824 | ENA
ProteomicsHLA class II ligandome of C1R BLCL cell line
HLA-DR, -DQ and -DP ligands from transfected C1R cells were isolated using LB3.1, SPVL3 and B721 antibodies respectively.
ORGANISM(S): Homo sapiens (Human) 
2021-08-18 | PXD025877 | Pride
Class ii C1r Dp Immunopeptidomics Dq Hla-dr 
UnknownComplement C1r serine protease contributes to kidney fibrosis.
Not available
S-EPMC6879941 | biostudies-literature
TranscriptomicsmRNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1r.
Keratinocyte-derived cutaneous squamous cell carcinoma (cSCC) is the most common metastatic skin cancer, and its incidence is increasing globally. Chronic inflammation has been recognized as a risk factor for cSCC and inflammation is a typical feature in the progression of premalignant actinic kerat...
ORGANISM(S): Homo sapiens 
2021-11-17 | GSE174626 | GEO
UnknownMolecular determinants of the substrate specificity of the complement-initiating protease, C1r.
Not available
S-EPMC3668718 | biostudies-literature
UnknownPeriodontal Ehlers-Danlos Syndrome Is Caused by Mutations in C1R and C1S, which Encode Subcomponents C1r and C1s of Complement.
Not available
S-EPMC5097948 | biostudies-literature
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