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ProteomicsSampling from proteome to HLA-DR ligandome
Comprehensive analysis of the complex nature of the Human Leukocyte Antigen (HLA) class II ligandome is of utmost importance to understand the basis for CD4+ T cell mediated immunity and tolerance. Here, we implemented important improvements in the analysis of the repertoire of HLA-DR-presented pept...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-24 | MSV000082848 | MassIVE
ProteomicsHLA class II ligandome from HOM-2 and JY cell lines (HLA-DR an HLA-DP ligands)
A high-throughput mass spectrometry analysis was used to identify more than 16,000 cell peptides bound to several HLA-DR and -DP class II molecules isolated from large amounts of two human cell lines (HOM-2 and JY).
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD028006 | Pride
Hla-dr Hla-dp 
TranscriptomicsGene expression profiles of CD4 T cells and CD45+ HLA-DR+ cells during experimental allergic rhinitis in humans.
Six patients with seasonal allergic rhinitis were challenged daily for 8 days with birch pollen extract. A mucosal biopsy was obtained from one nostril at basline (day 0) and from the other nostril after allergen challenge (day 9). The mucosal biopsies were digested into single cells, and then sorte...
ORGANISM(S): Homo sapiens 
2015-09-01 | E-GEOD-49782 | biostudies-arrayexpress
ProteomicsSampling from proteome to HLA-DR ligandome
Comprehensive analysis of the complex nature of the Human Leukocyte Antigen (HLA) class II ligandome is of utmost importance to understand the basis for CD4+ T cell mediated immunity and tolerance. Here, we implemented important improvements in the analysis of the repertoire of HLA-DR-presented pept...
ORGANISM(S): Homo sapiens (Human) 
2016-01-25 | PXD002951 | Pride
Ethcd Hcd Ligandome Hla class ii Etd Mhc class ii 
ProteomicsHLA-DR peptides from human BAL and EBV-transformed B cells
Optimization of the protocols for isolation HLA-DR (MHCII) peptides from human BAL.
ORGANISM(S): Homo sapiens (Human) 
2016-08-08 | PXD002439 | Pride
Bal Sarcoidosis Hla-dr peptides 
GenomicsTranscriptome analysis of HLA-DR(+) HSPCs and HLA-DR(-) HSPCs in aplastic anemia patients
Transcriptome analysis of HLA-DR(+) HSPCs and HLA-DR(-) HSPCs in aplastic anemia patients
PRJNA761999 | ENA
ProteomicsHLA-DR ligands from BLCLs 9022 and 9087
HLA-DR-bound peptides eluted from B-lymphoblastoid cell lines 9022 and 9087.
ORGANISM(S): Homo sapiens (Human) 
2020-03-11 | PXD017682 | Pride
Human Blcl Immunopeptidome Hla class ii Hla-dr 
ProteomicsThe immunopeptidome of HLA-DR from PBMC
Quantifiying the impact of initial cell counts on the identified HLA-DR immunopeptidome of PBMC.
ORGANISM(S): Homo sapiens (Human) 
2021-08-23 | PXD023032 | Pride
Pbmc Hla-ii Immunopeptidome Human blood Hla-dr 
TranscriptomicsImmune related gene expression comparison between human CD14+ HLA-DR-neg/low MDSC vs CD14+ HLA-DR-high control monocytes
Myeloid-derived suppressor cells (MDSC) is a heterogeneous population of cells that can negatively regulate T-cell function. As opposed to murine MDSC, which are characterized as Gr-1+CD11b+ cells, human MDSC are not so clearly defined due to lack of specific markers. Our lab has previously identifi...
ORGANISM(S): Homo sapiens 
2011-09-08 | E-GEOD-32001 | biostudies-arrayexpress
ProteomicsHLA-DR MAPPs Assay in moDCs From 8 Donors Loaded With Infliximab
MHC-associated peptide proteomics (MAPPs) enables direct identification of peptides naturally processed and presented by APCs, providing experimental evidence for antigen processing and HLA class II presentation. In this dataset published in PMID: 41085630, an HLA-DR–focused MAPPs workflow was used ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-13 | PXD074155 | Pride
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