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TranscriptomicsGenome-wide gene expression profile analysis in pulmonary sarcoidosis
We hypothesized that tissue genome-wide gene expression analysis, coupled with gene network analyses of differentially expressed genes, would provide novel insights into the pathogenesis of pulmonary sarcoidosis. Keywords: Disease state analysis Genome-wide gene expression profiles were compared in...
ORGANISM(S): Homo sapiens 
2009-06-11 | E-GEOD-16538 | biostudies-arrayexpress
TranscriptomicsMolecular profiling and gene expression analysis in cutaneous sarcoidosis (CS)
Cutaneous sarcoidosis skin provides relatively non invasive access to granulomatous sarcoidosis tissue. Twenty participants were enrolled: 15 with active CS and 5 healthy volunteers. Microarray analyses comparing non-LS and healthy volunteer skin with LS showed several thousand genes differentially ...
ORGANISM(S): Homo sapiens 
2011-10-12 | E-GEOD-32887 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling of sarcoidosis Treg cells
Sarcoidosis is characterized by exaggerated immune response to unknown agent and can affect different organs. One of the main players in the pathology of the disease are regulatory T cells (Tregs), however up to date there are no insides on the possible molecular alterations of this particular cell ...
ORGANISM(S): Homo sapiens 
2018-09-29 | E-MTAB-6590 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human peripheral blood cells from sarcoidosis patients vs. healthy controls
Sarcoidosis + Follow-up 6 month after
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1907 | biostudies-arrayexpress
ProteomicsBALF exosomes - Pulmonary Sarcoidosis is Associated With Exosomal Vitamin D-Binding Protein and Inflammatory Molecules
Using 8-plex iTRAQ labelling exosmes isolated from bronchial lavage (BALF) were analyzed by LC-MS/MS. The measurements compared control subjects with sarcoidosis patients (15 in all) ; five with löfgrens syndrome and 10 with regular sacroidosis
ORGANISM(S): Homo sapiens (Human) 
2016-09-27 | PXD001808 | Pride
Sarcoidosis Exosome Balf 
TranscriptomicsGene and microRNA expression in pulmonary tuberculosis and sarcoidosis
Common gene and microRNA expression patterns in TB and sarcoidosis Gene and microRNA expression analysis of whole blood RNA from tuberculosis and sarcoidosis patients and healthy controls
ORGANISM(S): Homo sapiens 
2012-04-14 | E-GEOD-34608 | biostudies-arrayexpress
TranscriptomicsSarcoidosis-specific markers from whole blood gene expression
We hypothesized that microarray analyses of whole blood gene expression would identify patterns of gene expression useful in the diagnosis for sacroidosis and identify inflammatory mediators relevant to the underlying pathophysiology. We analyzed whole blood RNA from 37 patients with sarcoidosis, 20...
ORGANISM(S): Homo sapiens 
2011-08-10 | E-GEOD-19314 | biostudies-arrayexpress
TranscriptomicsHuman whole blood microarray study to compare patients with tuberculosis, sarcoidosis, pneumonia, and lung cancer (validation)
This study used whole blood transcriptional signatures from patients with tuberculosis, sarcoidosis and healthy controls. There were 8 TB, 11 sarcoidosis and 23 healthy controls
ORGANISM(S): Homo sapiens 
2013-10-31 | E-GEOD-42825 | biostudies-arrayexpress
TranscriptomicsHuman whole blood microarray study to compare patients with tuberculosis, sarcoidosis, pneumonia, and lung cancer (test)
This study used whole blood transcriptional signatures from patients with tuberculosis compared to those with similar pulmonary diseases, sarcoidosis, pneumonia and primary lung cancer. TB and sarcoidosis had similar signatures that were distinct from pneumonia and lung cancer. There were 11 TB, 25 ...
ORGANISM(S): Homo sapiens 
2013-10-31 | E-GEOD-42826 | biostudies-arrayexpress
ProteomicsAlterations in the membrane-associated proteome of alveolar macrophages in sarcoidosis
Here we have performed qualitative profiling of the membrane-associated proteome of alveolar macrophages in sarcoidosis patients and healthy individuals with the aim to identify specific proteins and pathways involved in sarcoidosis pathology.
ORGANISM(S): Homo sapiens (Human) 
2016-12-23 | PXD000752 | Pride
Sarcoidosis Inflammation Isoelectric focusing Alveolar macrophages Membrane-associated proteins 
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