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TranscriptomicsTranscription profiling of human fibroblasts grown in petri dishes vs. attached to a tissue engineering scaffold sampled at 7 timepoints.
A goal of tissue engineering is to produce a scaffold material that will guide cells to differentiate and regenerate functional replacement tissue at the site of injury. Little is known about how cells respond on a molecular level to tissue engineering scaffold materials. In this work we used oligon...
ORGANISM(S): Homo sapiens 
2007-10-26 | E-GEOD-6432 | biostudies-arrayexpress
OtherQuantification of Extracellular Matrix Proteins from a Rat Lung Scaffold to Provide a Molecular Readout for Tissue Engineering.
Data from ProteomeXchange, PXD ID: PXD001213. File: 20121108_Native_Frac3_Lung01_Run03.mzml. Published as part of . From the Abstract: {{i}} ... To support organ engineering efforts, we developed a targeted proteomics method to extract and quantify extracellular matrix components from tissues. Our ...
ORGANISM(S): Rat 
GPM32310006954 | GPMDB
Resource Reanalysis 
TranscriptomicsTranscription profiling time series of the growth of human IMR-90 cells seeded on a collagen/chondroitin sulfate tissue engineering scaffold
A series of chips with some repeated measurments. Each chip represents a pool of 4 collagen/chondroitin sulfate tissue engineering scaffold meshes seeded with 1 x 10^6 IMR-90 Human Fibroblasts. mRNA was isolated at 30 minutes, 1, 2, 4, 8, 12, 24, 48, and 72 hours after seeding.
ORGANISM(S): Homo sapiens 
2007-12-13 | E-GEOD-409 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CD34+ hematopoietic cells grown in suspension culture or in a collegen I matrix
CD34+ hematopoietic stem/progenitor cells (HSC) reside in the bone marrow in close vicinity to the endosteal bone surface, surrounded by osteoblasts, stromal cells and various extracellular matrix molecules. We utilized a bioartificial matrix containing fibrillar collagen I, the major matrix compone...
ORGANISM(S): Homo sapiens 
2007-12-12 | E-GEOD-3003 | biostudies-arrayexpress
ProteomicsProteomics of tissue matrix scaffold derived from decellularized mice mammary tissues, LC-MS/MS
This project is intended to identify the compositions of the tissue matrix scaffold (TMS) generated from the extracellular matrix (ECM) of decellularized NON-SCID mice breast tissues (DBT). Since ECM is the physicochemical support for the cells living in the tissue microenvironment, it is important ...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-26 | PXD005697 | Pride
Ecm Breast/mammary tissue Tissue matrix scaffold Tms Decellularization Lc-ms/ms 
ProteomicsIncreased levels of extracellular matrix proteins in extracellular vesicles from brains of aged mice.
Extracellular vesicles (EVs) have several functions in the brain, serving as a mode of intercellular communication and as a pathway for disposal of cellular debris. While these functions serve to maintain healthy brain function, they may also contribute to diseases affecting the brain. EVs also chan...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD052797 | Pride
Aging Extracellular vesicles Extracellular matrix Lcms Mouse model Proteomics 
ProteomicsHuman testicular matrix
ITo derive a scaffold from human testis for the purpose of tissue engineering and regenerative medicine, we developed a method to produce a cytocompatible decellularized testicular matrix (DTM) while maintaining the native tissue-specific characteristics and components. The potential benefits of tis...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-14 | MSV000079582 | MassIVE
ProteomicsHuman testicular matrix - Derivation and characterization of a cytocompatible scaffold from human testis
ITo derive a scaffold from human testis for the purpose of tissue engineering and regenerative medicine, we developed a method to produce a cytocompatible decellularized testicular matrix (DTM) while maintaining the native tissue-specific characteristics and components. The potential benefits of tis...
ORGANISM(S): Homo sapiens (Human) 
2015-01-30 | PXD001524 | Pride
Testicular structure Extracellular matrix 3d cell culture 
ProteomicsCol4a5 mouse glomerular extracellular matrix
Alport mouse model (Col4a5) have been submitted for proteomic analysis. Glomeruli have been isolated from mouse kidneys, extracellular matrix has been enriched and analysed by mass spectrometry.
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD022227 | Pride
Extracellular matrix Matrix signature Glomerulus Basement mmebrane 
ProteomicsProteomic characterization of native and decellularized rat submandibular gland scaffolds prepared using the S3T1 protocol
Salivary gland hypofunction lacks effective regenerative treatment, and organ-specific decellularized extracellular matrix scaffolds represent a promising biomaterial platform for tissue engineering. In this study, rat submandibular glands were decellularized using a rapid S3T1 workflow consisting o...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-04-21 | PXD077315 | Pride
Extracellular matrix scaffold Proteomics Dia Rat Submandibular gland Salivary gland tissue engineering Decellularization Lc-ms/ms 
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