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TranscriptomicsRNA-seq of PBT2-Zn treated Fusobacterium nucleatum cells in vitro
To investigate the effect of the Zn ionophore, PBT2, on the transcriptomic response of Fusobacterium nucleatum ATCC 25586, RNA was extracted from bacterial samples which had been treated as follows: Untreated (0.006% DMSO v/v), DMSO-Zn treated (0.006% DMSO v/v + 200 uM ZnSO4), or PBT2-Zn treated (0....
ORGANISM(S): Fusobacterium nucleatum 
2021-07-15 | E-MTAB-8681 | biostudies-arrayexpress
TranscriptomicsCharacterization of the autoaggregation response of Fusobacterium nucleatum
Fusobacterium nucleatum is a Gram negative oral bacterial species associated with periodontal disease progression. This species is perhaps best known for its ability to adhere to a vast array of other bacteria and eukaryotic cells. Numerous studies of F. nucleatum have examined various coaggregation...
ORGANISM(S): Fusobacterium nucleatum 
2009-10-15 | E-GEOD-18554 | biostudies-arrayexpress
TranscriptomicsComparison of Fusobacterium Nucleatum stimulated and unstimulated neutrophils
Neutrophils are known to be stimulated by different periodontal bacteria to produce reactive oxygen species and cytokines. It is inportant to investigate the gene changes made by bacteria of importance, of which, for periodontal disease, fusobaterium nucleatum is one. we used microarrays to investig...
ORGANISM(S): Homo sapiens 
2010-07-20 | E-GEOD-20151 | biostudies-arrayexpress
TranscriptomicsThe effect of blood on Fusobacterium nucleatum
Fusobacterium nucleatum is a Gram-negative oral bacterial species associated with periodontal disease progression. As periodontal disease progresses, it is known F. nucleatum coaggregated with blood is frequently detected in the gingival crevice. However, it is largely unknown whether these interact...
ORGANISM(S): Fusobacterium nucleatum subsp. nucleatum ATCC 25586 
2012-09-01 | E-GEOD-36410 | biostudies-arrayexpress
ProteomicsA global survey of small RNA interactors identifies KhpA and KhpB as major RNA-binding proteins in Fusobacterium nucleatum
The common oral microbe Fusobacterium nucleatum has recently gained attention when it was found to colonize tumors throughout the human body. Fusobacteria are also interesting in regard to bacterial RNA biology as these early-branching species encode many small noncoding RNAs (sRNAs) but lack homolo...
ORGANISM(S): Fusobacterium nucleatum subsp. nucleatum ATCC 23726 
2024-02-08 | PXD046416 | Pride
Rbp  kh-domain  fusobacterium nucleatum  srna 
ProteomicsQuantitative Proteomic Analysis of Extracellular Matrix Extracted from Mono- and Dual-Species Biofilms of Fusobacterium nucleatum and Porphyromonas gingivalis
Background The Gram-negative bacteria Fusobacterium nucleatum and Porphyromonas gingivalis are associated with periodontitis and members of a complex microbial biofilm. The self-produced extracellular polymeric matrix (EPM) of biofilms generally consists of lipids, exopolysaccharides, nucleic acids...
ORGANISM(S): Porphyromonas gingivalis ATCC 33277 Fusobacterium nucleatum subsp. nucleatum ATCC 25586 
2017-03-16 | PXD004888 | Pride
Bacterial biofilms Label-free quantitative tandem mass spectrometry Fusobacterium nucleatum Extracellular polymeric matrix Proteomics. Porphyromonas gingivalis 
ProteomicsProteomic analysis of Fusobacterium nucleatum and Porphyromonas gingivalis biofilms and planktonic cultures when grown as mono- or dual-species models
Bacterial cells in biofilms adopt a profoundly different phenotype than their planktonic counterparts. The Gram-negative bacteria Fusobacterium nucleatum and Porphyromonas gingivalis are pathogens associated with oral biofilm and periodontal disease. In this study, we identified and functionally cha...
ORGANISM(S): Porphyromonas gingivalis ATCC 33277 Fusobacterium nucleatum subsp. nucleatum ATCC 25586 
2021-09-22 | PXD008288 | Pride
Bacterial biofilms Label-free quantitative proteomics. Biofilm phenotype Planktonic bacteria Fusobacterium nucleatum Porphyromonas gingivalis 
ProteomicsIdentification of the cellular component interacted with F. nucleatum.
We incubated F. nucleatum lysates with biotinylated proteins from KRAS p.G12D, KRAS p.G13D and KRAS WT cells respectively. Subsequent western blot analysis showed that three candidate proteins from F. nucleatum might interact with KRAS p.G12D cells. The bands of interest were then submitted for mass...
ORGANISM(S): Fusobacterium nucleatum CTI-1 
2024-01-25 | PXD048686 | Pride
Kras g12d fn1859 
GenomicsFusobacterium nucleatum
Fusobacterium nucleatum Genome sequencing
PRJNA831657 | ENA
ProteomicsThe Periodontal Pathogen Fusobacterium nucleatum Exacerbates Alzheimer’s Pathogenesis via Specific Pathways
Alzheimer’s disease (AD) is the most common form of dementia in older adults and has a devastating impact on the patient’s quality of life, which creates a significant socio-economic burden for the affected individuals and their families. In recent years, studies have identified a relationship betwe...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD033147 | Pride
F. nucleatum Mouse model Alzheimer’s disease Inflammation Periodontitis 
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