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ProteomicsHeteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP Type C
Neurodegenerative diseases are characterised by the abnormal filamentous assembly of specific proteins in the central nervous system1. Human genetic studies established a causal role for protein assembly in neurodegeneration2. However, the underlying molecular mechanisms remain largely unknown, whic...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055345 | Pride
Frontotemporal dementia Neurodegenerative disease Tdp-43 and tmem106b 
UnknownStructure of TDP-43 amyloid filaments from type A FTLD-TDP (individual 2)
Not available
EMPIAR-11428 | biostudies-other
UnknownStructure of TDP-43 amyloid filaments from type A FTLD-TDP (individual 3)
Not available
EMPIAR-11429 | biostudies-other
UnknownStructure of TDP-43 amyloid filaments from type A FTLD-TDP (individual 1)
Not available
EMPIAR-11438 | biostudies-other
ProteomicsHepG2 GalNAc-T1/2 Bump-and-hole secretome glycopeptide data
Engineered GalNAc-T glycosyltransferases were used to incorporate a chemically modified GalNAC analog into the secretome of HepG2 cells. The chemical modification included a bioorthogonal alkyne tag that allowed for introduction of a clickable, acid-cleavable biotin-picolyl-azide. Glycoproteins were...
ORGANISM(S): Homo sapiens (Human) 
2020-04-22 | PXD018048 | Pride
Human Bioorthogonal Galnac-t Liver Glycopeptide Click Secretome Hepg2 
UnknownStructure of pathological TDP-43 filaments from ALS with FTLD (Individual 1, frontal cortex)
Not available
EMPIAR-10830 | biostudies-other
UnknownStructure of pathological TDP-43 filaments from ALS with FTLD (Individual 1, motor cortex)
Not available
EMPIAR-10831 | biostudies-other
UnknownStructure of pathological TDP-43 filaments from ALS with FTLD (Individual 2, frontal cortex)
Not available
EMPIAR-10832 | biostudies-other
ProteomicsqXL-MS of insulin resistance in C2C12 myotubes
C2C12 myotubes were made insulin resistant with 0.5 mM palmitic acid for 24 h along with non-treated controls and then each group stimulated with or without 100 nM insulin for 30 min (n=4 each). Cells were then cross-linked with 2 mM of tPhoX for a further 30 min in the presence of insulin and the r...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-29 | PXD077371 | Pride
Tmt C2c12 Tphox 
ProteomicsMetaproteomic analysis of nine coral species with and without Stony Coral Tissue Loss Disease (SCTLD)
Florida’s coral reefs are currently experiencing a multi-year disease-related mortality event, that has resulted in massive die-offs in multiple coral species. Approximately 21 species of coral, including both Endangered Species Act-listed and the primary reef-building species, have displayed tissue...
ORGANISM(S): Colpophyllia natans Orbicella annularis Diploria labyrinthiformis Montastraea cavernosa Dichocoenia stokesii Orbicella faveolata Pseudodiploria strigosa Meandrina meandrites Pseudodiploria clivosa 
2021-05-21 | PXD026192 | Pride
Sctld Metaproteomics Corals 
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