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TranscriptomicsSingle cell experiment with iPS derived neural stem cells and 28 day differentiated neuronal cells from healthy individual and NRXN1-a biallelic deletion individual
iPS cell derived neural stem cells and differentiated cells from one healthy individual and one indivudal carrying NRXN1-a biallelic deletion investigated with single cell RNA-sequencing. Celltype characterization and comparison revealed variations between stem cell identity and in cell differentiat...
ORGANISM(S): Homo sapiens 
2019-07-20 | E-MTAB-7744 | biostudies-arrayexpress
GenomicsHuman iPS-derived astroglia from a stable neural precursor state improved functionality compared to conventional astrocytic models
Human iPS-derived astroglia from a stable neural precursor state improved functionality compared to conventional astrocytic models
PRJNA429370 | ENA
ProteomicsSQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation
Neurodegenerative disorders are an increasingly common and irreversible burden on society, often affecting the ageing population, but their aetiology and disease mechanisms are poorly understood. Studying monogenic neurodegenerative diseases, with known genetic cause, provides an opportunity to unde...
ORGANISM(S): Homo sapiens (Human) 
2019-03-05 | PXD006647 | Pride
Mitophagy Neurodifferentiation Hypoxia Mitochondria Oxidative stress Neuroepithelial-like stem cells P62 Sqstm1 Neuronal development 
UnknownTamoxifen-predictive value of gene expression signatures in premenopausal breast cancer: data from the randomized SBII:2 trial.
Not available
S-EPMC10540453 | biostudies-literature
UnknownDementia remains the major predictor of death among octogenarians. A study of two population cohorts of 85-year-olds examined 22 years apart.
Not available
S-EPMC8159837 | biostudies-literature
UnknownDNA methylation at retrotransposons protects the germline by preventing NRF1-mediated activation
Not available
S-SCDT-10_1038-S44319-025-00526-1 | biostudies-other
UnknownLoss-of-function in RBBP5 results in a syndromic neurodevelopmental disorder associated with microcephaly.
Not available
S-EPMC11648989 | biostudies-literature
UnknownZAK-beta is activated by cell compression and mediates contraction-induced MAPK signaling in muscle
Not available
S-SCDT-EMBOJ-2022-111650 | biostudies-other
UnknownMortality after surgery in Europe: a 7 day cohort study.
Not available
S-EPMC3493988 | biostudies-literature
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