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TranscriptomicsA Regulatory Pathway Involving Notch1/β-Catenin/Isl1 Determines Cardiac Progenitor Cell Fate
The regulation of multipotent cardiac progenitor cell (CPC) expansion and subsequent differentiation into cardiomyocytes, smooth muscle, or endothelial cells is a fundamental aspect of basic cardiovascular biology and cardiac regenerative medicine. However, the mechanisms governing these decisions r...
ORGANISM(S): Mus musculus 
2009-05-13 | E-GEOD-15232 | biostudies-arrayexpress
UnknownPotential Impacts of Interleukin-17A Promoter Polymorphisms on the EGFR Mutation Status and Progression of Non-Small Cell Lung Cancer in Taiwan.
Not available
S-EPMC8002550 | biostudies-literature
UnknownHuayu Jiedu Fang Protects Ovarian Function in Mouse with Endometriosis Iron Overload by Inhibiting Ferroptosis.
Not available
S-EPMC9448539 | biostudies-literature
UnknownCancer-associated fibroblast-derived interleukin-1β activates protumor C-C motif chemokine ligand 22 signaling in head and neck cancer.
Not available
S-EPMC6726685 | biostudies-literature
MetabolomicsPRODH regultes naive pluripotency by influencing mitochondrial oxidative phosphorylation (Untargeted metabolomics)

Naïve human embryonic stem cells (hESCs) that resemble the pre-implantation epiblasts are fueled by a combination of aerobic glycolysis and oxidative phosphorylation, but their mitochondrial regulators are poorly understood. Here we report that, proline dehydrogenase (PRODH), a mitochondria-local...

2024-02-12 | MTBLS7840 | MetaboLights
UnknownOptimizing bone health in people living with HIV: insights from a network meta-analysis of randomized controlled trials.
Not available
S-EPMC11876934 | biostudies-literature
UnknownSex-specific pathways among tri-allelic serotonin transporter polymorphism, trait neuroticism and generalized anxiety disorder.
Not available
S-EPMC7595742 | biostudies-literature
ProteomicsUSP20, a Super-enhancer Regulated Gene, Promotes Acute Myeloid Leukemia Progression through CTNNB1 Deubiquitination
Acute Myeloid Leukemia (AML) is a heterogeneous hematologic malignancy driven by genetic and epigenetic alterations, where super-enhancers (SEs) play key oncogenic roles, representing promising therapeutic targets in AML. Through H3K27ac ChIP-seq profiling of 7 AML cell lines and 13 primary samples,...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD066445 | Pride
Usp20  super-enhancer  aml  ctnnb1  as1517499 
UnknownThe influence of atrial fibrillation on the mortality of incident ESRD patients undergoing maintenance hemodialysis.
Not available
S-EPMC6992232 | biostudies-literature
TranscriptomicsAssessment of hematopoietic failure due to RPL11 deficiency in a zebrafish model of DiamondM-bM-^@M-^SBlackfan anemia by deep sequencing
To comprehensively reflect the impact of RPL11 deficiency on the transcriptome of zebrafish embryos, we collected 40M-bM-^@M-^S50 RPL11-deficient and MO control zebrafish embryos at 48 hpf from separate experiments and constructed two mRNA-seq sequencing libraries in parallel. High-throughput sequen...
ORGANISM(S): Danio rerio 
2014-01-21 | E-GEOD-51326 | biostudies-arrayexpress
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