Sort   by:  
 Page size 
ProteomicsPDGFRalpha/beta heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation
The platelet-derived growth factor receptor (PDGFR) family of receptor tyrosine kinases consists of two receptors, PDGFRalpha and PDGFRbeta, that homodimerize and heterodimerize upon ligand binding. Here, we tested the hypothesis that differential internalization and trafficking dynamics of the vari...
ORGANISM(S): Homo sapiens (Human) 
2025-04-25 | PXD048421 | Pride
Global proteomics Silac Pdgfr Hcc15 
TranscriptomicsTranscriptional targets of Trps1 in vibrissae
Mutations in TRPS1 cause trichorhinophalangeal syndrome types I and III, which are characterized by sparse scalp hair in addition to craniofacial and skeletal abnormalities. Trps1 is a vertebrate transcription factor containing nine zinc-finger domains, including a GATA-type zinc finger through whi...
ORGANISM(S): Mus musculus 
2011-12-22 | E-GEOD-33766 | biostudies-arrayexpress
ProteomicsPrimary mouse embryonic palatal mesenchyme LC-MS/MS
To identify proteins phosphorylated by Akt downstream of PI3K-mediated PDGFRalpha signaling, we immunoprecipitated Akt phosphorylation substrates from PDGF-AA-treated primary mouse embryonic palatal mesenchyme (MEPM) lysates and analyzed the peptides by nano LC-MS/MS.
ORGANISM(S): Mus musculus (Mouse) 
2019-06-04 | PXD000779 | Pride
Mouse Primary embryonic palatal mesenchyme Lc-ms/ms 
Sort   by:  
 Page size