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ProteomicsInvestigating the multi-mechanistic anticancer effects of 4-bisarylurea thiouracil derivatives in breast cancer cells
The study reports the synthesis of a series of 4-bisarylureathiouracil derivatives (6a-e) for potential use in breast cancer treatment. In vitro cytotoxicity was assessed in MCF-7 and MDA-MB-231 human breast cancer cell lines, revealing significant anti-cancer activity. Compound 6e exhibited the hig...
ORGANISM(S): Homo sapiens (Human) 
2025-07-19 | PXD065576 | Pride
Apoptosis Anti-inflammatory Breast cancer Cytotoxicity Proteomics 
UnknownEfficacy of Ketamine versus Magnesium Sulphate as Adjuvants to Levobupivacaine in Ultrasound Bilevel Erector Spinae Block in Breast Cancer Surgery (a Double-Blinded Randomized Controlled Study).
Not available
S-EPMC9514291 | biostudies-literature
UnknownEvaluation of the Mechanical, Physical, and Anti-Fungal Properties of Flax Laboratory Papersheets with the Nanoparticles Treatment.
Not available
S-EPMC7014466 | biostudies-literature
UnknownDiscovery and characterization of phenoxyacetic acid derivatives as potential antiepileptic agents.
Not available
S-EPMC12531995 | biostudies-literature
UnknownThe Delta variant wave in Tunisia: Genetic diversity, spatio-temporal distribution and evidence of the spread of a divergent AY.122 sub-lineage.
Not available
S-EPMC9846204 | biostudies-literature
ProteomicsDistinct spectrum of ciliopathic diseases results from de novoTUBB4B variants through differential effects on organelle-specific microtubules
Microtubules are ancient and highly conserved polymers composed of alpha and beta tubulin heterodimers. Their dynamic remodelling drives diverse cellular processes from organelle trafficking and chromosome segregation to templating more stable structures like those of centrioles and ciliary axonemes...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2024-01-30 | PXD036304 | Pride
Tubulin Cilia 
UnknownStoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort.
Not available
S-EPMC10549897 | biostudies-literature
UnknownCiliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules.
Not available
S-EPMC7616230 | biostudies-literature
UnknownGlobal hospital-based disease management of acute diverticulitis: a prospective, international cohort study.
Not available
S-EPMC12512976 | biostudies-literature
UnknownEffects of nintedanib in patients with limited cutaneous systemic sclerosis and interstitial lung disease.
Not available
S-EPMC10907814 | biostudies-literature
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