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ProteomicsAge-dependent increase in Schmidt-Lanterman incisures and a Cadm4 associated membrane skeletal complex in fatty acid 2-hydroxylase deficient mice, a mouse model of spastic paraplegia SPG35
Fatty acid 2-hydroxylase (FA2H) is responsible for the synthesis of 2-hydroxylated fatty acids, which are a building block of sphingolipids. This 2-hydroxylated sphingolipids can be found in various tissues such as brain, spinal cord, skin, testis, ovary, kidney, stomach, or intestine with a notably...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-22 | PXD030244 | Pride
Isobaric labelling Schmidt-lanterman incisures Mice Hereditary spastic paraplegia type 35 Sphingolipids Neurodegeneration Sciatic nerves Disease model Fa2h Tmt Time course Myelin Fatty acid hydroxylation Pns Fatty acid 2-hydroxylase 
UnknownLactones from Unspecific Peroxygenase-Catalyzed In-Chain Hydroxylation of Saturated Fatty Acids.
Not available
S-EPMC10353034 | biostudies-literature
UnknownCrystal structure of H2O2-dependent cytochrome P450SPalpha with its bound fatty acid substrate: insight into the regioselective hydroxylation of fatty acids at the alpha position.
Not available
S-EPMC3191035 | biostudies-literature
UnknownTransferrin promotes fatty acid oxidation and liver tumor growth through PHD2-mediated PPARα hydroxylation in an iron-dependent manner.
Not available
S-EPMC11804496 | biostudies-literature
UnknownKinetic analysis of lauric acid hydroxylation by human cytochrome P450 4A11.
Not available
S-EPMC4188250 | biostudies-literature
UnknownFunctional analysis of the LACERATA gene of Arabidopsis provides evidence for different roles of fatty acid omega -hydroxylation in development.
Not available
S-EPMC55514 | biostudies-literature
UnknownIdentification of a crucial amino acid implicated in the hydroxylation/desaturation ratio of CpFAH12 bifunctional hydroxylase.
Not available
S-EPMC6771796 | biostudies-literature
UnknownHomologous electron transport components fail to increase fatty acid hydroxylation in transgenic Arabidopsis thaliana.
Not available
S-EPMC3893003 | biostudies-literature
UnknownA mammalian fatty acid hydroxylase responsible for the formation of alpha-hydroxylated galactosylceramide in myelin.
Not available
S-EPMC1186713 | biostudies-literature
ProteomicsOmega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice
Soybean oil consumption is increasing worldwide and parallels the rise in obesity. Rich in unsaturated fats, especially linoleic acid, soybean oil is assumed to be healthy, and yet it induces obesity, diabetes, insulin resistance and fatty liver in mice. Here, we show that the genetically modified s...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-06-08 | MSV000081149 | MassIVE
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