Sort   by:  
 Page size 
Escherichia coli FBP1 Genome sequencing and assembly
To determine whether FBP1 has previously unknown tumor suppressor activity, we immunoprecipitated FBP1 from Huh7 HCC cells and performed mass spectrometry analyses of FBP1 immunoprecipitants.
ORGANISM(S): Homo sapiens (Human) 
2024-03-12 | PXD050213 | Pride
FBP1 is a rate limiting enzyme in glucogenogenesis and FBP1 expression changes cells to oxidative phosphorylation. Expressing FBP1 in basal-like breast cancer cells, which lack the expression of this enzyme, will identify the genes involved in glycolysis. FBP1 was expressed in MDA-MB231 and Hs578T c...
ORGANISM(S): Homo sapiens 
FBP1 overexpression in MDA-MB-231 breast cancer cells
An EZH2-FBP1 Feedback Circuitry Promotes Tumorigenesis in Gluconeogenic Tissues
FBP1 acts as a protein phosphatase to dephosphorylate histone H3
Data from study comparing liver tissue of mice deficient of hepatic Fbp1. Lack of Fbp1 reveals Fbp1 and NRF2 as important protein regulations in metabolic dysfunction-associated steatohepatitis (MASH).
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-08-19 | MSV000095646 | MassIVE
Widespread use of the ancient drug salicylate for diabetes in humans has been prevented by challenging side effects of the drug, and continuing uncertainty about the relevant enzyme target(s), against which other drugs could then be developed. Here, we identify fructose-1,6-bisphosphatase 1 (FBP1) a...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-26 | PXD053975 | Pride
Lysine methyltransferase 5A (KMT5A) is the sole mammalian enzyme known to catalyze the monomethylation of histone H4 lysine 20 (H4K20mel) and nonhistone proteins such as p53, which are involved in the occurrence and progression of many cancers. Our study aimed to determine the function of KMT5A in i...
ORGANISM(S): Homo Sapiens 
Fructose 1,6 bisphosphatase the key enzyme of gluconeogenesis has emerged as a potential metabolic tumor suppressor. In breast cancer distinct FBP1 expression levels are found depending on subtype. In MDA-MB-231 FBP1 expression is suppressed. To get more insight into potential functions of FBP1 we i...
ORGANISM(S): Homo sapiens 
2023-10-02 | GSE244288 | GEO
Sort   by:  
 Page size