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ProteomicsSubstrate Trapping Proteomics Reveals Targets of the βTrCP2/FBXW11 Ubiquitin Ligase
We inhibited the proteosome to ‘trap’ ubiquitylated substrates on the SCFFBXW11 E3 complex. Comparative mass spectrometry analysis of immunopurified FBXW11 protein complexes before and after proteosome inhibition revealed known and putatively novel substrates.
ORGANISM(S): Homo sapiens (Human) 
2014-10-24 | PXD001062 | Pride
Btrc Fbxw11 E3 ubiquitin ligase 
GenomicsFbxw11 regulates macrophage polarization and enhances the anti-leukemia activity
Fbxw11 regulates macrophage polarization and enhances the anti-leukemia activity
PRJNA1402246 | ENA
GenomicsSingle-cell RNA Sequencing Facilitates Quantitative Analysis of Fbxw11 overexpressed hematopoietic stem/progenitor cells
Single-cell RNA Sequencing Facilitates Quantitative Analysis of Fbxw11 overexpressed hematopoietic stem/progenitor cells
PRJNA673833 | ENA
UnknownFBXW11 inhibits tumorigenesis by ubiquitinating YB1 in hepatocarcinoma.
Not available
S-EPMC12433413 | biostudies-literature
TranscriptomicsFbxw11 regulates macrophage polarization and enhances the anti-leukemia activity
investigate the effects of Fbxw11 on macrophage phenotype and function, providing experimental evidence for understanding the potential role of Fbxw11 in anti-leukemia immunity.
ORGANISM(S): Mus musculus 
2026-01-21 | GSE316297 | GEO
TranscriptomicsGene expression changes in Fbxw11 variants overexpressed in L1210 cell line
We compared the transcriptomic changes in L1210 cells when Fbxw11 variants were overexpressed. In order to study the function of Fbxw11 in L1210 cells.
ORGANISM(S): Mus musculus 
2018-03-29 | GSE101725 | GEO
UnknownFbxw11 impairs the repopulation capacity of hematopoietic stem/progenitor cells.
Not available
S-EPMC9188144 | biostudies-literature
UnknownExpression of FBXW11 in normal and disease-associated osteogenic cells.
Not available
S-EPMC10243156 | biostudies-literature
TranscriptomicsSingle-cell RNA Sequencing Facilitates Quantitative Analysis of Fbxw11 overexpressed hematopoietic stem/progenitor cells
We compared the transcriptomic changes in hematopoietic stem/progenitor cells (LSK) when Fbxw11 overexpressed. In order to study the function of Fbxw11 in hematopoietic stem/progenitor cells.
ORGANISM(S): Mus musculus 
2022-06-15 | GSE160643 | GEO
UnknownSubstrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.
Not available
S-EPMC4295375 | biostudies-literature
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