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MetabolomicsTherapeutic effects of traditional Chinese medicine compound Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota

Hua-Feng-Dan is a traditional Chinese medicine compound used to treat ischemic stroke, but little is known about its therapeutic mechanism. This study explored whether and how the mechanism involves readjustment of gut microbiota. Rats were subjected to middle cerebral artery occlusion as a model...

2025-01-06 | MTBLS10818 | MetaboLights
TranscriptomicsSaccharomyces cerevisiae: DSB mapping by Break-chip in a two-color experiment (G1 control vs. S phase samples)
Break-chip (microarray-based double strand break mapping) analysis of mec1 cells recovering from 200 mM hydroxyurea in the presence or absence of 0.8 micromolar bathophenanthroline sulfonate (BPS). We asked if the presence of an iron chelator, BPS, during cell recovery from transient exposure to 200...
ORGANISM(S): Saccharomyces cerevisiae 
2015-01-12 | E-GEOD-64446 | biostudies-arrayexpress
TranscriptomicsssDNA in S phase compared to G1 phase at different timepoints
To identify origins of replication in Lachancea waltii by mapping regions of ssDNA that are enriched in S phase. L. waltii cells are grown in the presence of hydroxyurea, which slows replication forks and causes the accumulation of ssDNA at the replication fork.
ORGANISM(S): Lachancea waltii 
2012-05-09 | E-GEOD-35253 | biostudies-arrayexpress
ProteomicsS. japonicum exosome-like vesicles LC-MS/MS
Secreted extracellular vesicles play an important role in pathogen-host interactions. Increased knowledge of schistosome extracellular vesicles could provide insights into schistosome-host interactions and enable the development of novel intervention strategies to inhibit parasitic processes and les...
ORGANISM(S): Schistosoma japonicum (Blood fluke) 
2018-10-27 | PXD003364 | Pride
S. japonicum exosome lc-ms/ms 
TranscriptomicsTranscription profiling of S. cerevisiae to identify Upf1p-associated transcripts in S. cerevisiae
The goal of this experiment was to identify transcripts associated with the S. cerevisiae Upf1 protein. Experiment Overall Design: The RNA population from four independent pairs of Upf1p-TAP and mock affinity selections were analyzed by using Affymetrix Yeast Genome S98 Arrays.
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-9486 | biostudies-arrayexpress
MetabolomicsExploratory Multi-Omics Analysis of Gut Microbiota and Fecal Metabolites in Relation to Serum S-Equol Levels in Older Adults with Osteoporosis from a Tropical Community: A Pilot Study

This study aimed to investigate fecal metabolomic profiles associated with osteoporosis and serum S-equol levels in community-dwelling older adults from a tropical region of China. Fecal samples were collected from participants classified as osteoporosis or non-osteoporosis based on bone mineral ...

2026-02-10 | MTBLS13855 | MetaboLights
TranscriptomicsTranscription profiling of S. cerevisiae response to the antifungal compound sampangine
Sampangine, a plant-derived alkaloid found in the Annonaceae family, exhibits strong inhibitory activity against the opportunistic fungal pathogens Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus. In the present study, transcriptional profiling experiments coupled with the analy...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-11 | E-GEOD-10073 | biostudies-arrayexpress
ProteomicsProteome Profiling of Endogenous and Potential S-nitrolysation in Colorectal Cancer
Background. As a common cancer with high incidence rate and mortality, colorectal cancer (CRC) is seriously threatening human health. Nitric oxide (NO) mediated protein S-nitrosylation (SNO) is of great significance in the occurrence and development of CRC, melanoma, breast cancer and other cancers....
ORGANISM(S): Homo Sapiens 
2023-01-13 | PXD039376 |
UnknownFabrication of Glutaraldehyde Vapor Treated PVA/SA/GO/ZnO Electrospun Nanofibers with High Liquid Absorbability for Antimicrobial of Staphylococcus aureus.
Not available
S-EPMC10004850 | biostudies-literature
UnknownRadical S-Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S.
Not available
S-EPMC8934444 | biostudies-literature
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