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MetabolomicsModification of erythrocyte membrane phospholipid composition in preterm newborns with retinopathy of prematurity: The omegaROP study

N-3 polyunsaturated fatty acids (PUFAs) may prevent retinal vascular abnormalities observed in oxygen-induced retinopathy, a model of retinopathy of prematurity (ROP). In the OmegaROP prospective cohort study, we showed that preterm infants who will develop ROP accumulate the n-6 PUFA arachidonic...

2022-09-07 | MTBLS4219 | MetaboLights
ProteomicsProteomic Comparisoadsfasn of Intact and Fetoscopy-Induced Fetal Membrane Sites
Iatrogenic preterm premature rupture of fetal membranes (iPPROM) following fetoscopic interventions remains a major barrier to the advancement of fetal therapies. The mechanisms underlying iPPROM are poorly understood, but the inability of fetal membrane (FM) defects to heal spontaneously likely pla...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD067401 | Pride
Fetal membrane Ttts Human Ipprom 
ProteomicsBioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium
In the current study we examined several proteomic- and RNA-Seq-based datasets of cardiac-enriched, cell-surface and membrane-associated proteins in human fetal and mouse neonatal ventricular cardiomyocytes. By integrating available microarray and tissue expression profiles along with MGI phenotypic...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2020-11-17 | PXD017732 | Pride
Bioinformatics Therapeutics Cardiomyocytes Membrane proteins Heart disease 
GenomicsBuprenorphine induces human fetal membrane sterile inflammation
Buprenorphine induces human fetal membrane sterile inflammation
PRJNA1190073 | ENA
ProteomicsFetal immunomodulatory environment following cartilage injury – the key to cartilage regeneration?
Fetal cartilage fully regenerates following injury while in adult mammals cartilage injury leads to osteoarthritis (OA). OA is characterized by cartilage breakdown and joint inflammation and associated with significant pain and socioeconomic costs. As no clinically satisfactory treatment is availabl...
ORGANISM(S): Ovis aries 
2022-02-17 | PXD027486 | Pride
Cartilage Macrophage Regeneration Inflammation Neutrophil Fetal Immunomodulation 
UnknownProgesterone receptor membrane components: key regulators of fetal membrane integrity.
Not available
S-EPMC7876665 | biostudies-literature
UnknownIn vivo Sealing of Fetoscopy-Induced Fetal Membrane Defects by Mussel Glue.
Not available
S-EPMC10015749 | biostudies-literature
TranscriptomicsTranscription profiling by array of week by week changes in the transcriptional ontogeny of first trimester human fetal mesenchymal stem cells
We characterized the developmental transciptome of first trimester MSC from fetal bone marrow (BM) compared to that from adnexal structures across multiple time points (8wks-12wks). Please note: DevelopmentalStage (Early =weeks 8-9, Late = weeks 10-12)
ORGANISM(S): Homo sapiens 
2014-11-24 | E-TABM-1224 | biostudies-arrayexpress
TranscriptomicsReconstructing the human first trimester fetal-maternal interface using single cell transcriptomics - whole genome sequencing
To explore the interactions between the range of maternal and fetal placental cell types present, we profiled the transcriptomes of more than 50,000 single cells from matched first trimester samples of maternal blood and decidua, as well as fetal cells from the placenta itself. Demuxlet was used to ...
ORGANISM(S): Homo sapiens 
2018-10-17 | E-MTAB-7304 | biostudies-arrayexpress
TranscriptomicsMaternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response.
Maternal immune activation is a risk factor for the development of schizophrenia and autism. Infections during pregnancy activate the mother's immune system and alter the fetal environment with sub-sequence effects of CNS function and behavior in the offspring, but the cellular and molecular links b...
ORGANISM(S): Rattus norvegicus 
2012-07-25 | E-GEOD-34058 | biostudies-arrayexpress
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