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Formalin-fixed, paraffin-embedded (FFPE) is the most common method for preserving tissue material in the clinic with millions of specimens stored in biobanks around the world. However, FFPE samples present challenges for molecular profiling, including proteomics. Nonetheless, optimized sample prepar...
ORGANISM(S): Homo sapiens (Human) 
2026-05-26 | PXD072014 | Pride
Formalin-fixed, paraffin-embedded (FFPE) is the most common method for preserving tissue material in the clinic with millions of specimens stored in biobanks around the world. However, FFPE samples present challenges for molecular profiling, including proteomics. Nonetheless, optimized sample prepar...
ORGANISM(S): Homo sapiens (Human) 
2026-05-26 | PXD071948 | Pride
Formalin fixation and paraffin-embedding (FFPE) is the most common method to preserve human tissue for clinical diagnosis and FFPE archives represent an invaluable resource for biomedical research. Proteins in FFPE material are stable over decades but their efficient extraction and streamlined analy...
ORGANISM(S): Homo sapiens (Human) 
2020-04-02 | PXD017269 | Pride
Formalin-fixed, paraffin-embedded (FFPE) archives underpin dermatopathology and translational oncology, enabling clinically annotated melanoma cohorts, but cohort-scale proteomics remains limited by labor and variability in upstream processing. We established a plate-scale, acoustic FFPE proteomics ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-09 | PXD074156 | Pride
Most human tumor tissues that are obtained for pathology and diagnostic purposes are forma-lin-fixed and paraffin embedded (FFPE). To perform quantitative proteomics of FFPE samples, paraffin has to be removed and formalin-induced crosslinks have to be reversed prior to prote-olytic digestion. A c...
ORGANISM(S): Homo sapiens (Human) 
2022-05-19 | PXD031946 | Pride
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