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Fibroblasts produce the majority of collagen in the heart and are thought to regulate extracellular matrix (ECM) turnover. However, the in vivo role of fibroblasts in structuring the basal ECM network is poorly understood. To examine the effects of fibroblast loss on the microenvironment in the adul...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD021741 | Pride
Fibroblasts produce the majority of collagen in the heart and are thought to regulate extracellular matrix (ECM) turnover. However, the in vivo role of fibroblasts in structuring the basal ECM network is poorly understood. To examine the effects of fibroblast loss on the microenvironment in the adul...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD021739 | Pride
Our previous study revealed that the basic helix-loop-helix transcription factor Hand2 is a downstream target of progesterone signaling in mouse uterine stroma at the time of implantation. Further, conditional deletion of Hand2 in mouse uterus leads to implantation failure due to impaired uterine ep...
ORGANISM(S): Mus musculus 
Targeted PDGFRα+ fibroblast ablation exacerbates pathologic features of asthma in house dust mite-induced allergenic asthma model
single cell transcriptomic analysis of embyronic hearts with fibroblast ablation
Our preliminary study revealed that the homeobox transcription factors, Msx1 and Msx2, are expressed in the mouse uterus during early pregnancy. Further, conditional deletion of Msx1 and Msx2 in mouse uterus leads to implantation failure due to impaired uterine epithelial receptivity. To identify th...
ORGANISM(S): Mus musculus 
Our preliminary study revealed that the homeobox transcription factors, Msx1 and Msx2, are expressed in the mouse uterus during early pregnancy. Further, conditional deletion of Msx1 and Msx2 in mouse uterus leads to implantation failure due to impaired uterine epithelial receptivity. To identify th...
ORGANISM(S): Mus musculus 
2014-07-20 | GSE30966 | GEO
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