Many bacteria, often associated with eukaryotic hosts and of relevance for biotechnological applications, harbor a multipartite genome composed of more than one replicon. Biotechnologically relevant phenotypes are often encoded by genes residing on the secondary replicons. A synthetic biology approa...
The objective of the experiment was to compare the secretome of wild type mouse prostate oganoids (WT-mPrOs) to the one obtained from mPrOs bearing a doxycycline inducible ERG expression vector system (ERGM40 mPrOs).