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ProteomicsRegulation of mitophagy by Fis1 and Fascin1-organized actin
Mitophagy, the autophagic degradation of mitochondria, plays a central role in controlling the quality and quantity of mitochondria, thereby ensuring cellular health. The mitochondrial outer membrane protein Fis1 is important for several types of mitophagy, but its mechanism of action remains unclea...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-07 | PXD062948 | Pride
Mitophagy Fascin1 Fis1 Mitochondria Actin filaments 
GenomicsMitochondrial Fission 1 (FIS1) knockdown effect on the transcriptome of leukemia cell line MOLM-13 cells
Mitochondrial Fission 1 (FIS1) knockdown effect on the transcriptome of leukemia cell line MOLM-13 cells
PRJNA464347 | ENA
GenomicsPrimary hepatocyte transcriptional response to Fis1 and Drp1 over-expression by adenovirus
Primary hepatocyte transcriptional response to Fis1 and Drp1 over-expression by adenovirus
PRJNA717245 | ENA
GenomicsMitochondrial Fission 1 (FIS1) knockdown effect on the transcriptome of primary human acute myeloid leukemia (AML) cells
Mitochondrial Fission 1 (FIS1) knockdown effect on the transcriptome of primary human acute myeloid leukemia (AML) cells
PRJNA464346 | ENA
GenomicsMitochondrial Fission 1 (FIS1) knockdown effect on the H3K27Ac status of leukemia cell line MOLM-13 cells
Mitochondrial Fission 1 (FIS1) knockdown effect on the H3K27Ac status of leukemia cell line MOLM-13 cells
PRJNA464339 | ENA
TranscriptomicsMitochondrial Fission 1 (FIS1) knockdown effect on the transcriptome of leukemia cell line MOLM-13 cells
To explore the function of Mitochondrial Fission 1 (FIS1) in acute myeloid leukemia (AML), we used shRNA to knock down the expression of FIS1 in leukemia cell line MOLM-13 cells and performed RNA-seq experiments to profile transcriptional changes upon FIS1 depletion.
ORGANISM(S): Homo sapiens 
2018-06-01 | GSE114111 | GEO
TranscriptomicsMitochondrial Fission 1 (FIS1) knockdown effect on the transcriptome of primary human acute myeloid leukemia (AML) cells
To explore the function of Mitochondrial Fission 1 (FIS1) in acute myeloid leukemia (AML), we used shRNA to knock down the expression of FIS1 in primary human AML cells and performed RNA-seq experiments to profile global gene expression changes upon FIS1 depletion.
ORGANISM(S): Homo sapiens 
2018-06-01 | GSE114109 | GEO
TranscriptomicsMitochondrial Fission 1 (FIS1) knockdown effect on the H3K27Ac status of leukemia cell line MOLM-13 cells
To examine if loss of FIS1 would alter the H3K27Ac status of leukemic cells, we used shRNA to knock down the expression of FIS1 in leukemic cell line MOLM-13 cells and performed H3K27Ac CHIP-seq to characterize any changes in the H3K27Ac marks upon loss of FIS1.
ORGANISM(S): Homo sapiens 
2018-06-01 | GSE114106 | GEO
TranscriptomicsPrimary hepatocyte transcriptional response to Fis1 and Drp1 over-expression by adenovirus
RNA-seq analysis of Ad-LacZ, Ad-Fis1 and Ad-Drp1 infected primary hepatocyte.
ORGANISM(S): Mus musculus 
2021-03-26 | GSE169630 | GEO
UnknownDirect binding of the dynamin-like GTPase, Dnm1, to mitochondrial dynamics protein Fis1 is negatively regulated by the Fis1 N-terminal arm.
Not available
S-EPMC3046406 | biostudies-literature
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