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ProteomicsRegulation of mitophagy by Fis1 and Fascin1-organized actin
Mitophagy, the autophagic degradation of mitochondria, plays a central role in controlling the quality and quantity of mitochondria, thereby ensuring cellular health. The mitochondrial outer membrane protein Fis1 is important for several types of mitophagy, but its mechanism of action remains unclea...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-07 | PXD062948 | Pride
Mitophagy Fascin1 Fis1 Mitochondria Actin filaments 
UnknownFascin1 promotes cell migration of mature dendritic cells.
Not available
S-EPMC3526951 | biostudies-literature
UnknownFascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development.
Not available
S-EPMC8217270 | biostudies-literature
UnknownStructural insights into full-length human fascin1: a target for cancer treatment.
Not available
S-EPMC12210192 | biostudies-literature
ProteomicsCytokine profile of mature WT bone marrow-derived dendritic cells and fascin1 knockout bone marrow-derived dendritic cells
Cytokines secreted by WT and fascin1 KO BM-DCs maturated by LPS were determined by RayBio Quantibody mouse Th17 array1. Fascin1 KO BM-DCs show reduced secretion of several cytokines including IL-6.
ORGANISM(S): Mus musculus 
2021-05-12 | GSE174285 | GEO
UnknownNew role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells.
Not available
S-EPMC7062870 | biostudies-literature
GenomicsCytokine profile of mature WT bone marrow-derived dendritic cells and fascin1 knockout bone marrow-derived dendritic cells
Cytokine profile of mature WT bone marrow-derived dendritic cells and fascin1 knockout bone marrow-derived dendritic cells
PRJNA729095 | ENA
UnknownThe FDA-Approved Antiviral Raltegravir Inhibits Fascin1-Dependent Invasion of Colorectal Tumor Cells In Vitro and In Vivo.
Not available
S-EPMC7921938 | biostudies-literature
UnknownEffects of imipramine on cancer patients over-expressing Fascin1; description of the HITCLIF clinical trial.
Not available
S-EPMC10570506 | biostudies-literature
GenomicsGene expression alteration in murine chondrogenic cell line ATDC5 cells by IL-1β and Fascin1 inhibitor NP-G2-044 treatment
Gene expression alteration in murine chondrogenic cell line ATDC5 cells by IL-1β and Fascin1 inhibitor NP-G2-044 treatment
PRJNA973014 | ENA
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