Sort   by:  
 Page size 
ProteomicsMetalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Removal
Cytotoxicity of DNA-protein crosslinks (DPCs) is ascribed largely to their ability to block the progression of DNA replication fork. DPCs are frequently occurring in cells, either as a consequence of metabolism or exogenous agents. The mechanism of DPCs removal is not completely understood. Here, we...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080743 | MassIVE
TranscriptomicsTranscriptional hallmarks of heterogeneous neural stem cell niches of the subventricular zone.
Throughout postnatal life in mammals, neural stem cells (NSCs) are located in the subventricular zone (SVZ) of the lateral ventricles. The greatest diversity of neuronal and glial lineages they generate occurs during early postnatal life in a region-specific manner. In order to evaluate potential he...
ORGANISM(S): Mus musculus 
2015-04-07 | E-GEOD-60905 | biostudies-arrayexpress
ProteomicsAn updated proteomic analysis of Drosophila hemolymph after bacterial infection
Using an in-depth Mass Spectrometry based proteomics approach, we provide a comprehensive characterization of the hemolymphatic proteome of adult flies upon bacterial infection. We detected and quantified changes in abundance of several known immune regulators and effectors, including multiple antim...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-05-07 | PXD058897 | Pride
Serine proteases Hemolymph Mass spectrometry Immunity Mitochondria Drosophila melanogaster Antimicrobial peptides Toll pathway Lc-ms/ms Imd pathway 
ProteomicsDrosophila hemolymph infected with Spiroplasma poulsonii
We investigated the effect of Spiroplasma infection on Drosophila hemolymph protein content using Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS). To this end, we extracted total hemolymph from uninfected and infected 10 days old females. At this age, Spiroplasma is already present at high...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-05-04 | PXD024340 | Pride
Lc-msms Drosophila Spiroplasma Endosymbiosis 
ProteomicsUnraveling the Bombus terrestris hemolymph, a readout of the immune response to microbial infections, through complementary mass spectrometry approaches
Pollinators are of crucial importance for maintaining biodiversity in ecosystems and for agriculture, including the Buff-tailed bumblebee Bombus terrestris. The health decline in these populations is thought to be linked to various abiotic and biotic stressors. In the hope of protecting these popula...
ORGANISM(S): Bombus terrestris (Buff-tailed bumblebee) (Apis terrestris) 
2023-05-10 | PXD035224 | Pride
Proteomics Response to pathogens Immune response Bumblebee Bee health Molecular fingerprints Pollinators Bacterial infections 
UnknownJEWELFISH: 24-month results from an open-label study in non-treatment-naive patients with SMA receiving treatment with risdiplam.
Not available
S-EPMC11319388 | biostudies-literature
UnknownComorbidities in Mild WAS/XLT Require Lifelong Follow-Up and Consideration of Definitive Treatment.
Not available
S-EPMC12516653 | biostudies-literature
TranscriptomicsTuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses
Tuberculosis (TB) remains a major public health problem and we lack a comprehensive understanding of how Mycobacterium tuberculosis (M. tb) infection impacts host immune responses. We compared, at two timepoints, the induced immune response to TB antigen, BCG and IL-1β stimulation between latently M...
ORGANISM(S): Homo sapiens 
2022-11-05 | E-MTAB-12379 | biostudies-arrayexpress
UnknownFully automated sequential immunofluorescence (seqIF) for hyperplex spatial proteomics.
Not available
S-EPMC10562446 | biostudies-literature
Unknownbrainlife.io: a decentralized and open-source cloud platform to support neuroscience research.
Not available
S-EPMC11093740 | biostudies-literature
Sort   by:  
 Page size