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GenomicsDNAseq of human Ewing cell line - CADO-ES1
Ewings Sarcoma (ES) belongs to the group of bone cancers defined by the existence of a certain EWS-ETS fusion gene. In this study we use the model cell line CADO-ES1 (EWSR1-ERG fusion gene) to characterize the genomic structure in respect to CNV and fusion gene events.
ORGANISM(S): Homo sapiens 
2017-10-02 | E-MTAB-6111 | biostudies-arrayexpress
TranscriptomicsRNAseq of human Ewing, MSC, fibroblast cell lines - A side population of Ewing cells exhibits stem cell properties
Ewings Sarcoma (ES) belongs to the group of bone cancers defined by the existence of a certain EWS-ETS fusion gene. In this study we use the model cell line CADO-ES1 (EWSR1-ERG fusion gene) to characterize the tumor biology of a versatile ES side-population (SP). We aim to compare SP- and non-SP-cel...
ORGANISM(S): Homo sapiens 
2017-10-31 | E-MTAB-6067 | biostudies-arrayexpress
MetabolomicsMetabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS
As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...
2021-10-12 | MTBLS2130 | MetaboLights
TranscriptomicsOxidative burden and mitochondrial dysfunction in a mouse model of Rett syndrome
To identify the detailed molecular causes of the mitochondrial dysfunction, oxidative burden and more vulnerable redox balance in Rett mouse hippocampus, we screened for differential gene expression in the hippocampal CA1 subfield of adult male mice. A whole mouse genome microarray was performed to ...
ORGANISM(S): Mus musculus 
2012-08-31 | E-GEOD-32870 | biostudies-arrayexpress
ProteomicsChaperonin CCT Checkpoint Function in Basal Transcription Factor TFIID Assembly
TFIID is a cornerstone of eukaryotic gene regulation. Distinct TFIID complexes with unique subunit composition exist and several TFIID subunits are shared with other complexes, conveying intricate cellular decision making to control subunit allocation and functional assembly of this essential transc...
ORGANISM(S): Homo sapiens (Human) 
2022-03-02 | PXD011211 | Pride
Proteomics Crystal structure Tfiid Chaperonin cct 
TranscriptomicsRNA-seq analysis of ID8 ovarian cancer cells after harvest from malignant ascites
Sequencing of mRNA from ID8 tumor cells and ID8 tumor cells harvested from ascites of mice 11 weeks after intra peritoneal inoculation show acquisition of cancer stem cell-like features in ascitic tumor cells.
ORGANISM(S): Mus musculus 
2020-01-06 | E-MTAB-8140 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of macrophages from normal and tumor-infiltrated omentum
Sequencing of mRNA from tissue-resident and tumor-associated macrophages in murine omentum display distinct transcriptional profile between macrophage subset of different origin
ORGANISM(S): Mus musculus 
2020-01-06 | E-MTAB-8141 | biostudies-arrayexpress
UnknownPreoperative REM Sleep Behavior Disorder and Subthalamic Nucleus Deep Brain Stimulation Outcome in Parkinson Disease 1 Year After Surgery.
Not available
S-EPMC8672430 | biostudies-literature
UnknownImmunovirological status in people with perinatal and adult-acquired HIV-1 infection: a multi-cohort analysis from France.
Not available
S-EPMC10993179 | biostudies-literature
UnknownTherapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.
Not available
S-EPMC8362594 | biostudies-literature
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