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MetabolomicsMetabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS
As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...
2021-10-12 | MTBLS2130 | MetaboLights
TranscriptomicsIdentification of Xenotropic MuLV-related virus
This series includes 20 microarrays used to identify Xenotropic MuLV-related virus (XMRV) in a set of human prostate tumors associated with R462Q RNASEL variant (Urisman, et al. 2006). The series includes 19 prostate tumor samples (VP) and a cell line control (HeLa).
ORGANISM(S): Viruses 
2010-07-01 | E-GEOD-3607 | biostudies-arrayexpress
MetabolomicsUntargeted Metabolomics for Integrative Taxonomy: Metabolomics, DNA Marker-Based Sequencing, and Phenotype Bioimaging

Integrative taxonomy is a fundamental part of biodiversity and combines traditional morphology with additional methods such as DNA sequencing or biochemistry. Here, we aim to establish untargeted metabolomics for use in chemotaxonomy. We used three thallose liverwort species Riccia glauca

2026-01-30 | MTBLS4668 | MetaboLights
Proteomics- Deep proteomics network and machine learning analysis of human cerebrospinal fluid in Japanese encephalitis virus infection
- Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus, and leading cause of neurological infection in Asia and the Pacific, with recent emergence in multiple territories in Australia in 2022. Patients may experience devastating socioeconomic consequences; JEV infection (JE) predominantl...
ORGANISM(S): Homo sapiens (Human) 
2023-06-08 | PXD034789 | Pride
Arbovirus - neurological infection Encephalitis Tmt Central nervous system infection Japanese encephalitis virus Flavivirus Lao pdr Brain infection Meningitis Cerebrospinal fluid (csf) 
MetabolomicsHabitual Coffee Intake Shapes the Gut Microbiome and Modifies Host Physiology and Cognition: double-blind, randomised, parallel design

Coffee influences multiple physiological processes, including gut function, stress, cognition, and the microbiome. However, the mechanisms underlying these effects remain poorly understood. In this study, we examined coffee’s impact on the microbiota–gut–brain axis—a bidirectional communication p...

2026-03-26 | MTBLS13401 | MetaboLights
TranscriptomicsAntagonistic role of MBNL1 and LIN28 promotes specific alteration of pre-miR-1 processing and is associated with heart defects in DM
Myotonic dystrophy type 1 (DM1), the most common muscular dystrophy in adults, is caused by the expression of expanded CUG repeats, which sequester the MBNL1 RNA binding protein. Cardiac involvement, which is characterized by conduction defects and arrhythmias, is the second cause of death of DM1 pa...
ORGANISM(S): Homo sapiens 
2011-05-26 | E-GEOD-24109 | biostudies-arrayexpress
MetabolomicsHabitual Coffee Intake Shapes the Gut Microbiome and Modifies Host Physiology and Cognition

Coffee influences multiple physiological processes, including gut function, stress, cognition, and the microbiome. However, the mechanisms underlying these effects remain poorly understood. In this study, we examined coffee’s impact on the microbiota–gut–brain axis—a bidirectional communication p...

2026-04-07 | MTBLS13494 | MetaboLights
TranscriptomicsComparison of transcriptome between free-living and symbiotic cells of Frankia alni ACN14a
The actinobacteria Frankia alni is able to induce the formation of nodules on the root of a large spectrum of actinorhizal plants, where it converts dinitrogen to ammonia in exchange for plant photosynthates. In the present study, transcriptional analyses were performed on nitrogen-replete free-livi...
ORGANISM(S): Frankia alni ACN14a 
2010-09-12 | E-GEOD-18190 | biostudies-arrayexpress
MetabolomicsThe impact of nutritional supplementation on sweat metabolomic content
Sweat is emerging as a prominent biosource for real-time human performance monitoring applications. Although promising, sources of variability must be identified to truly utilize sweat for biomarker applications. In this proof-of-concept study, a targeted metabolomics method was applied to sweat col...
2021-03-15 | MTBLS2427 | MetaboLights
UnknownA double-blind, placebo-controlled trial assessing the efficacy of varenicline tartrate for alcohol dependence.
Not available
S-EPMC3914416 | biostudies-literature
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