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ModelsDallePezze2012 - TSC-independent mTORC2 regulation
DallePezze2012 - TSC-independent mTORC2 regulation This model is described in the article: A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation. Dalle Pezze P, Sonntag AG, Thien A, Prentzell MT, Gödel M, Fischer S, Neumann-Haefelin E, Huber TB, B...
2024-09-02 | BIOMD0000000581 | BioModels
ProteomicsExposure of a bovine rumen microbiome model to glyphosate
We evaluated the effects of pure glyphosate and the formulations Durano TF and Roundup® LB plus in different concentrations on rumen microbiota bioreactor model using the Rumen Simulation Technique (RUSITEC). Application of the compounds in three concentrations (0.1 mg/L, 1.0 mg/L or 10 mg/L, n = 4 ...
ORGANISM(S): Bos taurus (Bovine) 
2022-05-08 | PXD032166 | Pride
Bioreactor Intestinal microbiome Glyphosate Bovine rumen model 
TranscriptomicsExpression profiling after ICAP1 or constitutive active NOTCH1 over expression in human umbilical vein endothelial cells
ICAP1 (also known as ITG1BP1) is a protein interaction partner of beta1-integrins and the cerebral cavernous malformation protein 1 (CCM1, also known as KRIT1). In mice Icap1 plays an important role for bone development. The function of ICAP1 in endothelial cells is poorly understood. However, the i...
ORGANISM(S): Homo sapiens 
2010-07-30 | E-GEOD-18035 | biostudies-arrayexpress
TranscriptomicsGene expression profile after CCM1 over expression in human umbilical vein endothelial cells
CCM1 (also known as KRIT1) is critical regulator of endothelial cell biology. Mutations in CCM1 can lead to the formation of cerebral cavernous malformations (CCM). CCM lesions are frequent in the human population; however, their pathogenesis is poorly understood. This genome-wide expression analysi...
ORGANISM(S): Homo sapiens 
2010-06-16 | E-GEOD-18014 | biostudies-arrayexpress
GenomicsDAC University Hospital Cologne
Data Access Committee EGAC00001000361
EGAC00001000361 | EGA
ProteomicsCasID on RRM2 promoter region in neuroblastoma
dCas9-guided recruitment of the proximity ligation enzyme BirA* to the promoter region of RRM2 in SKNBE2c neuroblastoma cells.
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD029630 | Pride
Neuroblastoma Rrm2 Casid Bioid 
Genomicsena-DATASET-UKEssen-09-09-2015-10:54:33:815-144 - samples
In this dataset, 16 trios- primary tumor, relapse and corresponding normals- for patients with neuroblastoma are provided. For one patient, more than one relapse was available for the analyses.
EGAD00001001607 | EGA
GenomicsGenomes of Relapsing Neuroblastoma
Neuroblastoma is a malignancy of the developing sympathetic nervous system that is often lethal when relapse occurs, but the molecular mechanisms behind this process are poorly defined. We here used whole-exome sequencing, mRNA expression, array CGH and DNA methylation analysis to holistically chara...
EGAS00001001387 | EGA
GenomicsRelapsed and Primary Neuroblastoma DAC
Data Access Committee EGAC00001000373
EGAC00001000373 | EGA
ProteomicsM.musculus - Cerebral cortex, SC (Fornasieroetal,natcomm2018)
abundance based on Spectral counting, Interaction consistency score: 8.0, Coverage: 7
ORGANISM(S): 10090 
2018-00-00 | 494884207 | PAXDB
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