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MetabolomicsMulti-Omics Unveils Strain-Specific Neuroactive Metabolite Production Linked to Inflammation Modulation by Bacteroides and Their Vesicles

18 Bacteroidetes isoaltes were analyzed for their neuroactive potentail using un-targeted and targeted metabolomics. The bacteria were grown to stationary phase, the supernatant was separated and purified using 0.22 um filter. The metabolome from the supernatant was extracted using standard Metha...

2025-08-12 | MTBLS10526 | MetaboLights
MetabolomicsBioinspired Rhamnolipid Protects Wheat Against Zymoseptoria tritici Through Mainly Direct Antifungal Activity and Without Major Impact on Leaf Physiology

Rhamnolipids (RLs), glycolipids biosynthesized by the Pseudomonas and Burkholderia genera, are known to display various activities against a wide range of pathogens. Most previous studies on RLs focused on their direct antimicrobial activity, while only a few reports described t...

2022-06-21 | MTBLS4542 | MetaboLights
ProteomicsFunctional proteomics identifies acinus L as a direct insulin- and amino acid-dependent mTORC1 substrate
The serine/threonine kinase mammalian target of rapamycin (mTOR) governs growth, metabolism, and aging in response to insulin and amino acids (aa), and is often activated in metabolic disorders and cancer. Much is known about the regulatory signaling network around mTOR, but surprisingly few direct ...
ORGANISM(S): Homo sapiens (Human) 
2015-04-28 | PXD001196 | Pride
Lc-ms Silac Phosphoproteomics Human Mtor 
TranscriptomicsMycorrhizal Metabolome: L. bicolor :: P. trichocapra
Mycorrhizae, symbiotic interactions between soil fungi and tree roots, are ubiquitous in terrestrial ecosystems. The fungi contribute phosphorous, nitrogen and mobilized nutrients from organic matter in the soil and in return the fungus receives photosynthetically-derived carbohydrates. This union...
ORGANISM(S): Populus tremuloides 
2011-03-25 | E-GEOD-28157 | biostudies-arrayexpress
MetabolomicsStage-specific metabolic responses in blue mussels to marine shipping-related acoustic and chemical stressors revealed by nuclear magnetic resonance

Maritime traffic exposes coastal organisms to both acoustic disturbance and chemical pollution, yet how these stressors affect and interact across early developmental stages remains poorly understood. We investigated stage-specific metabolic responses of blue mussel (Mytilus edulis) larv...

2026-06-15 | MTBLS13945 | MetaboLights
TranscriptomicsMicroRNAs expression profiling during breast cancer progression
MicroRNAs (miRNAs) are known to be deregulated in human breast cancer (BC). The purpose of the current study was to investigate the expression of miRNAs in different stages of BC to assess their biological value in BC progression. MiRNA expression was assessed in a series of BC patients (n=7) with d...
ORGANISM(S): Homo sapiens 
2012-06-22 | E-GEOD-38867 | biostudies-arrayexpress
TranscriptomicsKetogenic Diet dependent Immunometabolic Reprogramming of human T cells
Purpose: We aim to identify transciptional changes of human CD4+/CD8+ T cells due to high fat low carbohydrate ketogenic diet (KD) in vivo. Method: Healthy volunteers conducted a 21 days ketogenic diet, limiting carbohydrate intake to <30g/day. Before the start (T0) and at the end (T1) of the diet, ...
ORGANISM(S): Homo sapiens 
2020-12-31 | GSE158407 | GEO
UnknownCirculating Tumor DNA Analysis to Assess Risk of Progression after Long-term Response to PD-(L)1 Blockade in NSCLC.
Not available
S-EPMC7299781 | biostudies-literature
ProteomicsDifferential assembly of RNP granules via activation of distinct dsRNA sensors by adenovirus mutants
Recognition of dsRNA triggers antiviral defense mediated by PKR and OAS3/RNase L pathways through translational arrest and RNA decay. This is accompanied by assembly of distinct cytoplasmic ribonucleoprotein (RNP) condensates termed stress granules (SGs) and RNase L-dependent bodies (RLBs). Here we ...
ORGANISM(S): Homo sapiens (Human) 
2026-07-10 | PXD075408 | Pride
Dna viruses Rnase l-dependent bodies (rlbs) Adenovirus 5 (ad5) Stress granules (sgs) 
UnknownEvaluation of Sensitivity to Endocrine Therapy Index (SET2,3) for Response to Neoadjuvant Endocrine Therapy and Longer-Term Breast Cancer Patient Outcomes (Alliance Z1031).
Not available
S-EPMC9357183 | biostudies-literature
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