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MetabolomicsMulti-Omics Unveils Strain-Specific Neuroactive Metabolite Production Linked to Inflammation Modulation by Bacteroides and Their Vesicles

18 Bacteroidetes isoaltes were analyzed for their neuroactive potentail using un-targeted and targeted metabolomics. The bacteria were grown to stationary phase, the supernatant was separated and purified using 0.22 um filter. The metabolome from the supernatant was extracted using standard Metha...

2025-08-12 | MTBLS10526 | MetaboLights
MetabolomicsMetabolic and gut microbial remodeling in captive Amur tigers under uniform feeding

Ultra-high-performance liquid chromatography (UHPLC) was conducted using a Vanquish UHPLC system (Thermo Fisher), coupled with a Q Exactive™ HF/Q Exactive™ HF-X mass spectrometer for liquid chromatography-mass spectrometry (LC-MS) analysis. To ensure...

2026-06-05 | MTBLS14159 | MetaboLights
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of transcriptomes in Multiple Myeloma (MM) cell lines treated with DMSO and Indirubin-3’-monoxime (I3MO)
To determine what signaling pathways are affected by I3MO in MM cells, 5 MM cell lines including ANBL6, ANBL6 BR, ARP1, RPMI-8226, and U266, were cultured with DMSO or 5/10µM I3MO for 48 h. Total RNAs of 2 x 10^6 cells for each sample were extracted using the RNeasy Mini Kit (Qiagen). The RNA yield ...
ORGANISM(S): Homo sapiens 
2022-01-26 | GSE194379 | GEO
UnknownA Pilot Study on Serial Nerve Ultrasound in Miller Fisher Syndrome.
Not available
S-EPMC7457056 | biostudies-literature
UnknownDescription of the male of Erromyrma Bolton & Fisher, 2016 (Hymenoptera, Formicidae).
Not available
S-EPMC10220497 | biostudies-literature
ProteomicsImplementing 1.5 mm internal diameter columns into microflow LC-MS bottom-up proteomics
In this study, we systematically evaluated the 1.5 mm i.d. column and compared its performance with 1.0 mm i.d. columns in analyzing protein samples of varying complexity using a conventional chromatographic system.
ORGANISM(S): Francisella tularensis subsp. holarctica (strain LVS) Homo sapiens (Human) 
2025-02-11 | PXD057525 | Pride
Proteomics Chromatography Columns Lc/ms Inner diameter 
GenomicsEffect of treatment with Levamisole 1 mM on activated human T-cells
Effect of treatment with Levamisole 1 mM on activated human T-cells
PRJNA962125 | ENA
ProteomicsMembrane mimetic thermal proteome profiling (MM-TPP) towards mapping membrane protein-ligand dynamic interactions
Integral membrane proteins (IMPs) are key targets for small-molecule therapeutics. However, robust, unbiased, and detergent-free methods to probe on- and off-target interactions within this protein class remain underdeveloped. Previously, we introduced the Peptidisc membrane mimetic (MM) for water-s...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-17 | PXD068828 | Pride
Membrane proteins Orbitrap exploris Mus musculus Membrane mimetic thermal proteome profiling Proteomics 
TranscriptomicsRNA-seq in WTC11 i3 lower-motor neurons with and without TDP-43 knockdown
Nuclear depletion and cytoplasmic aggregation of the RNA-binding protein TDP-43 is the hallmark of ALS, occurring in over 97% of cases. A key consequence of TDP-43 nuclear loss is the de-repression of cryptic exons. Motor neurons are the vulnerable cell-type in ALS and cryptic exons show variability...
ORGANISM(S): Homo sapiens 
2026-07-04 | E-MTAB-15433 | biostudies-arrayexpress
TranscriptomicsEffect of treatment with Levamisole 1 mM on activated human T-cells
To investigate the effects of levamisole treatment on in vitro activated human T-cells, we isolated T-cells from buffy coats from 3 donors. All buffy coats were collected from adult anonymous healthy blood donors (Sanquin Blood Supply, Amsterdam, The Netherlands) who provided written informed consen...
ORGANISM(S): Homo sapiens 
2025-04-26 | GSE230683 | GEO
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