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TranscriptomicsLocalization of Isw1-3xFLAG in wild-type yeast.
ChIP-chip assays to determine the localisation of 3xFLAG tagged Isw1 in wild-type yeast. Two color experiment. ChIP/Input. Biological replicates=3. Other data used in this study are provided in GEO Series GSE31015 and GSE31833.
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-06 | E-GEOD-31301 | biostudies-arrayexpress
TranscriptomicsChromatin remodelers Isw1 and Chd1 maintain chromatin structure during transcription by preventing histone exchange
This SuperSeries is composed of the following subset Series: GSE32042: Isw1 and Chd1 maintain chromatin organization during transcription GSE32043: Histone exchange in wildtype, isw1, chd1, isw1 chd1 and ioc4 yeast strains GSE32044: Histone H3 K36me3 in wildtype, isw1 and chd1 yeast strains GSE32045...
ORGANISM(S): Saccharomyces cerevisiae 
2012-07-24 | E-GEOD-32071 | biostudies-arrayexpress
ProteomicsInherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans
Age-related microangiopathy, also known as small vessel disease (SVD), causes damage to the liver, brain, kidney and retina. Based on the DNA damage theory of aging, we reasoned that genomic instability may underlie an SVD caused by dominant C-terminal variants in TREX1, the most abundant 3’-5’ DNA ...
ORGANISM(S): Homo sapiens (Human) 
2024-05-30 | PXD051905 | Pride
Brca1 Retinal vasculopathy with cerebral leukoencephalopathy Cerebroretinal vasculopathy Rvcl-s Rvcl Trex1 Interferon Inflamm-aging Herns Crv Dementia Dna damage response Small vessel disease Vasculopathy 
TranscriptomicsIsw1 and Chd1 maintain chromatin organization during transcription
ChIP-chip assays to determine the localization of 3xFLAG tagged Ioc4, Ioc3 & Isw1 in wildtype and set2 yeast. Two color experiment. ChIP/Input. Biological replicates=3.
ORGANISM(S): Saccharomyces cerevisiae 
2012-07-24 | E-GEOD-32042 | biostudies-arrayexpress
ProteomicsPost-translational modification mapping - CRK10 WT and crk10-A397T kinase domain
We have analysed the recombinant kinase domain of AtCRK10 (At4g23180) purified as an N-terminal His-tag from Escherichia coli cells by LC-MS/MS. Both the WT and the crk10-A39T7 mutant allele of the CRK10 kinase domain were analysed. Post-translational modifications were identified, and a MASCOT sear...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-07-20 | PXD023831 | Pride
Arabidopsis Cysteine-rich receptor-like kinase Kinase domain Crk10 
MetabolomicsCell-based and multi-omics profiling reveal dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei

Mitochondrial metabolic remodeling is a hallmark of the Trypanosoma brucei digenetic life cycle since the insect stage utilizes the cost-effective oxidative phosphorylation to generate ATP, while bloodstream cells switch to less energetically efficient aerobic glycolysis. Due to difficulties in a...

2020-08-20 | MTBLS1390 | MetaboLights
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