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TranscriptomicsA positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B mono-ubiquitylation to regulate transcript elongation in fission yeast
Transcript elongation by RNA polymerase II (RNAPII) is accompanied by conserved patterns of histone modification within transcribed regions, but it remains uncertain how these modifications influence, or are influenced by, properties of the elongation complex. Here we establish an intimate link betw...
ORGANISM(S): Schizosaccharomyces pombe 
2012-12-01 | E-GEOD-31070 | biostudies-arrayexpress
ProteomicsThe Triticale Mature Pollen and Stigma Proteomes – Assembling the Proteins for a Productive Encounter
Triticeae crops are major contributors to global food production and ensuring their capacity to reproduce and generate seeds is critical. However, despite their importance our knowledge of the proteins underlying Triticeae reproduction is severely lacking and this is not only true of pollen and sti...
ORGANISM(S): x Triticosecale 
2023-03-08 | PXD038905 | Pride
Proteomics Brassica Mass spectrometry Pollination Triticale Triticeae Stigma Pollen Itraq 
ProteomicsThe Brassica Mature Pollen and Stigma Proteomes: Preparing to Meet
Successful pollination brings together the mature pollen grain and stigma papilla to initiate an intricate series of molecular processes meant to eventually enable sperm cell delivery for fertilization and reproduction. At maturity, the pollen and stigma cells have acquired proteomes comprising the...
ORGANISM(S): Brassica carinata 
2021-03-13 | PXD017953 | Pride
Proteomics Pollen germination Mass spectrometry Pollen-stigma interactions Pollen tube growth Brassica carinata Stigma Pollen Itraq Lc-ms/ms 
UnknownA positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeast.
Not available
S-EPMC3410854 | biostudies-literature
Genomicsf7f7c45f-0307-419e-bae7-696385d2d5bd - samples
Paired-end DNA-seq FASTQ files from 16 carriers of the BMPR2 p.Arg491Gln mutation in a family affected by hereditary pulmonary arterial hypertension (HPAH). Whole genome sequencing of these samples was performed in an Illumina HiSeq 4000 instrument. Libraries were prepared using the Fisher PE Kit (K...
EGAD00001005756 | EGA
Genomics79221e59-a0ac-4e58-8391-656d4f4b15ed - samples
Paired-end DNA-seq BAM files from 16 carriers of the BMPR2 p.Arg491Gln mutation in a family affected by hereditary pulmonary arterial hypertension (HPAH). Whole genome sequencing of these samples was performed in an Illumina HiSeq 4000 instrument. Libraries were prepared using the Fisher PE Kit (Kap...
EGAD00001005757 | EGA
TranscriptomicsTbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex
Areas and layers of the cerebral cortex are specified by genetic programs that are initiated in progenitor cells and then, implemented in postmitotic neurons. Here, we report that Tbr1, a transcription factor expressed in postmitotic projection neurons, exerts positive and negative control over both...
ORGANISM(S): Mus musculus 
2010-07-27 | E-GEOD-22371 | biostudies-arrayexpress
Genomics53ec8527-2eaf-41b1-8781-c1eded8dc9ec - samples
VCF file from 16 carriers of the BMPR2 p.Arg491Gln mutation in a family affected by hereditary pulmonary arterial hypertension (HPAH). Whole genome sequencing of these samples was performed in an Illumina HiSeq 4000 instrument. Libraries were prepared using the Fisher PE Kit (Kapa Biosystems). BAM f...
EGAD00001005758 | EGA
ProteomicsSwitchgrass drought-induced leaf proteomics analysis
Switchgrass (Panicum virgatum) is a perennial crop producing deep roots thus highly tolerant to soil water deficit conditions. However, seedling establishment in field is very susceptible to prolonged and periodic drought stress. In this study, a “sandwich” system simulating a gradual water deletion...
ORGANISM(S): Panicum virgatum (Switchgrass) 
2016-08-09 | PXD004675 | Pride
Eight-plex-itraq  proteominer  drought tolerance 
MetabolomicsCritical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation (Shotgun lipidomics assays without inhibition)

During megakaryopoiesis, megakaryocytes (MK) undergo cellular morphological changes with strong modification of membrane composition and lipid signaling. Here we adopt a lipid-centric multi-omics approach to create a quantitative map of the MK lipidome during maturation and proplatelet formation....

2023-07-26 | MTBLS6082 | MetaboLights
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