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TranscriptomicsThe cytokine DIEDEL and a viral homologue suppress deleterious IMD-dependent gene expression in drosophila
Viral infection in Drosophila triggers inducible gene expression, but the function of many of these genes and the biological significance of their induction remain poorly understood. Here, we report the functional characterization of the gene Diedel, which is strongly induced following some viral in...
ORGANISM(S): Drosophila melanogaster 
2016-01-07 | E-GEOD-68174 | biostudies-arrayexpress
TranscriptomicsGene expression response to bacterial phagocytosis by S2 cells (control and eater RNAi knock down)
The Drosophila phagocytic receptor Eater is expressed specifically in phagocytic hemocytes. It contributes to host immune defense and is required for survival of bacterial infections. Eater is involved in recognition and phagocytosis of bacteria. We used microarrays to determine whether any gene exp...
ORGANISM(S): Drosophila melanogaster 
2011-08-24 | E-GEOD-31564 | biostudies-arrayexpress
ModelsFGF pathway of Drosophila Signalling Pathways
Fig 3B from the following paper\r\nLogical modelling of Drosophila signalling pathways. Mbodj A, Junion G, Brun C, Furlong EE, Thieffry D. Mol Biosyst. 2013 Sep;9(9):2248-58. doi:10.1039/c3mb70187e
3510 | Cell Collective
TranscriptomicspiRNA-mediated transgenerational inheritance of an acquired trait
The maintenance of genome integrity is an essential trait to the successful transmission of genetic information. In animal germ cells, piRNAs guide PIWI proteins to silence transposable elements (TEs) in order to maintain genome integrity. In insects, most of TE silencing in the germline is achieved...
ORGANISM(S): Drosophila melanogaster 
2012-04-13 | E-GEOD-34506 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila embryos shows the zinc finger protein Zelda plays a key role in the maternal to zygotic transition
In all animals, the initial events of embryogenesis are controlled by maternal gene products that are deposited into the developing oocyte. At some point after fertilization, control of embryogenesis is transferred to the zygotic genome in a process called the maternal to zygotic transition (MZT). D...
ORGANISM(S): Drosophila melanogaster 
2008-11-22 | E-GEOD-11231 | biostudies-arrayexpress
TranscriptomicsRNA-seq to investigate effect of what shock on procyclic-form trypanosomes - ribosomal subunit
These are the ribosomal subunit fractions from the polysome gradients. investigating effect of heat shock on procyclic-form trypanosomes.
ORGANISM(S): Trypanosoma brucei brucei 
2022-01-22 | E-MTAB-11314 | biostudies-arrayexpress
TranscriptomicsMicroRNA-dependent transposable element transcriptional silencing in Drosophila somatic ovarian cells [RNA-Seq]
RNAi-related silencing mechanisms concern as diverse biological processes as gene regulation, mostly via the miRNA pathway, and defense against molecular parasites, mainly controlled by the siRNA and the piRNA pathways. In Drosophila somatic ovarian cells, transposable elements (TEs) are repressed b...
ORGANISM(S): Drosophila melanogaster 
2015-04-08 | E-GEOD-60972 | biostudies-arrayexpress
GenomicsGenomic DNA T b. brucei and T. b. rhodesiense. Data for E-MTAB-3800
Genomic DNA T b. brucei and T. b. rhodesiense. These are actually paired reads but the files are unpaired
ORGANISM(S): Trypanosoma brucei 
2021-12-17 | E-MTAB-11303 | biostudies-arrayexpress
TranscriptomicsWild-type Lister 427 Bloodstream-form polysome profiles with ZC3H32 knock-down
Ran from polysomes of Lister 427 bloodstream forms, wild-type and a cell line with a double knockout and inducible ZC3H32, grown without tetracycline.
ORGANISM(S): Trypanosoma brucei 
2017-11-24 | E-MTAB-4558 | biostudies-arrayexpress
TranscriptomicsMicroRNA-dependent transposable element transcriptional silencing in Drosophila somatic ovarian cells [RIP-Seq]
RNAi-related silencing mechanisms concern as diverse biological processes as gene regulation, mostly via the miRNA pathway, and defense against molecular parasites, mainly controlled by the siRNA and the piRNA pathways. In Drosophila somatic ovarian cells, transposable elements (TEs) are repressed b...
ORGANISM(S): Drosophila melanogaster 
2015-04-08 | E-GEOD-60973 | biostudies-arrayexpress
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