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ProteomicsPerilous Sites: High basic Fibroblast Growth Factor level supplement Parkinson’s disease pathology and its Spread
Lewy body (LB) pathology and loss of dopaminergic neurons are imprints of Parkinson’s disease (PD). LBs are mainly comprised of alpha-Synuclein (Dijkstra et al., 2014). Strolling detection of LBs in brain regions contribute to progressive construct of PD pathology to which molecular mechanisms are n...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-07-21 | PXD015969 | Pride
Neuron Exosome Bfgf Rat 
TranscriptomicsSox4 links tumor suppression to accelerated aging in mice [Hair regeneration]
Sox4 is a transcription factor expressed during embryonic development and some adult tissues such as lymphoid organs, pancreas, intestine and skin. During embryogenesis, Sox4 regulates the survival of mesenchymal and neural progenitors, lymphocyte and myeloid differentiation, and pancreatic, bone an...
ORGANISM(S): Mus musculus 
2015-05-20 | E-GEOD-58153 | biostudies-arrayexpress
TranscriptomicsSox4 links tumor suppression to accelerated aging in mice [Telogen]
Sox4 is a transcription factor expressed during embryonic development and some adult tissues such as lymphoid organs, pancreas, intestine and skin. During embryogenesis, Sox4 regulates the survival of mesenchymal and neural progenitors, lymphocyte and myeloid differentiation, and pancreatic, bone an...
ORGANISM(S): Mus musculus 
2015-05-20 | E-GEOD-58154 | biostudies-arrayexpress
TranscriptomicsArray-CGH screening of pediatric T-lymphoblastic leukemias (n=73)
DNA copy-number profiling of 73 T-ALLs Keywords: Genetic modification Comparison of tumor DNA (tumor) versus control DNA (pool of lymphocyte DNA from 10 healthy donors). Whole-genome screening for DNA copy-number aberrations using array-based comparative genomic hybridization (aCGH). Tumor DNA label...
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-8738 | biostudies-arrayexpress
TranscriptomicsArray-CGH screening of medulloblastoma
DNA copy-number profiling of 80 primary medulloblastomas of different histologies Keywords: Genetic modification Comparison of tumor DNA (medulloblastoma) versus control DNA (pool of lymphocyte DNA from 10 healthy donors). Whole-genome screening for DNA copy-number aberrations using array-based comp...
ORGANISM(S): Homo sapiens 
2007-08-01 | E-GEOD-8634 | biostudies-arrayexpress
TranscriptomicsMurine hepatocellular carcinoma of MCL1-/- transgenic mice and age matched alb cre mice - 12 months old.
aCGH analysis of murine transgenic liver tissues affected with HCC, hybridized with age (12 months) and sex matched alb cre mice. Keywords: Array comparative genomic hybridization analysis (aCGH). Independent HCC of MCL1-/- mice were hybridized with pooled wt mice. Mcl‑1flox/flox mice (C57BL/6 ba...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-16580 | biostudies-arrayexpress
TranscriptomicsMurine hepatocellular carcinoma of AlbLTa/b transgenic mice and age matched C57BL/6 mice - 18 months old.
aCGH analysis of murine transgenic liver tissues affected with HCC, hybridized with age (18 months) and sex matched C57BL/6 mice. Moreover, 18months old C57BL/6 livers were hybridized with independent 18 months old C57BL/6 livers for control. Keywords: Array comparative genomic hybridization analy...
ORGANISM(S): Mus musculus 
2010-05-15 | E-GEOD-14467 | biostudies-arrayexpress
TranscriptomicsDeep Sequencing of the Porcine Endometrial Transcriptome on Day 14 of Pregnancy
In pigs, conceptus attachment to the uterine surface epithelium starts around day 14 of pregnancy preceded by a pronounced vascularization at the implantation zones, initiating the epitheliochorial placentation. To characterize the complex transcriptome changes in the endometrium in the course of in...
ORGANISM(S): Sus scrofa 
2013-03-07 | E-GEOD-43667 | biostudies-arrayexpress
TranscriptomicsDeep sequencing of the porcine endometrial transcriptome on day 12 of pregnancy
The porcine conceptus undergoes rapid differentiation and expansion of its trophoblastic membranes between Days 11 and 12 of gestation. Concomitant with trophoblast elongation, production of conceptus estrogen, the porcine embryonic pregnancy recognition signal increases. Conceptus attachment to the...
ORGANISM(S): Sus scrofa 
2013-10-31 | E-GEOD-48862 | biostudies-arrayexpress
TranscriptomicsArray-CGH screening of pediatric low-grade astrocytomas (n=66)
DNA copy-number profiling of 66 astrocytomas of WHO °I or °II Comparison of tumor DNA (tumor) versus control DNA (pool of lymphocyte DNA from 10 healthy donors). Whole-genome screening for DNA copy-number aberrations using array-based comparative genomic hybridization (aCGH). Tumor DNA labeled in Cy...
ORGANISM(S): Homo sapiens 
2007-08-10 | E-GEOD-8737 | biostudies-arrayexpress
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