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MetabolomicsMetabolic reaction network-based recursive metabolite annotation for untargeted metabolomics (Aging fruit fly positive mode)

Large-scale metabolite annotation is a challenge in liquid chromatogram-mass spectrometry (LC-MS)-based untargeted metabolomics. Here, we develop a metabolic reaction network (MRN)-based recursive algorithm (MetDNA) that expands metabolite annotations without the need for a comprehensive standard...

2019-03-22 | MTBLS612 | MetaboLights
MetabolomicsMetabolic reaction network-based recursive metabolite annotation for untargeted metabolomics (Aging fruit fly negative mode)

Large-scale metabolite annotation is a challenge in liquid chromatogram-mass spectrometry (LC-MS)-based untargeted metabolomics. Here, we develop a metabolic reaction network (MRN)-based recursive algorithm (MetDNA) that expands metabolite annotations without the need for a comprehensive standard...

2019-03-26 | MTBLS615 | MetaboLights
Transcriptomicshemocyte minus versus hemocyte plus drosophila embryos
Drosophila embryos that were lacking the hemocyte lineage were compared to wild-type embryos. Keywords: genetic modification Wild-type drosophila embryos were compared to serpent mutant embryos.
ORGANISM(S): Drosophila melanogaster 
2010-05-22 | E-GEOD-10208 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila early embryos and unfertized eggs to analyze mRNA decay patterns in early development
Comparison of expression profiles in early Drosophila embryos and unfertilised eggs (collection intervals: 30-60 min, 90-120 min and 150-180 min after egg laying). A complete summary file containing normalized data with FLYBASE CG gene identifiers, gene symbols and classifications can be found in E-...
ORGANISM(S): Drosophila melanogaster 
2011-02-11 | E-MEXP-2580 | biostudies-arrayexpress
TranscriptomicsExpression study of 'hemocyte minus vs hemocyte plus, and wounded vs unwounded hemocyte deficient' drosophila embryos
This SuperSeries is composed of the following subset Series: GSE10207: wounded versus nonwounded drosophila embryos GSE10208: hemocyte minus versus hemocyte plus drosophila embryos GSE10209: wounded vs unwounded hemocyte deficient embryos Keywords: SuperSeries Refer to individual Series
ORGANISM(S): Drosophila melanogaster 
2010-05-22 | E-GEOD-10225 | biostudies-arrayexpress
ProteomicsSILAC-based quantitative proteomic analysis of Drosophila gastrula stage embryos mutant for fibroblast growth factor signalin
Quantitative mass spectrometry-based proteomic analyses in combination with genetics provide powerful tools in developmental cell signaling research. Drosophila melanogaster is one of the most widely used genetic models for studying development and disease. Here we combined quantitative proteomics w...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-09-09 | PXD016438 | Pride
Silac Drosophila 
TranscriptomicsExpression data from Brakeless mutant Drosophila embryos
The Brakeless protein performs many important functions during Drosophila development, but how it controls gene expression is not understood. We previously showed that Brakeless can function as a transcriptional co-repressor. Here, we report transcriptional profiling of brakeless mutant embryos to i...
ORGANISM(S): Drosophila melanogaster 
2015-08-24 | E-GEOD-60048 | biostudies-arrayexpress
GenomicsSex comb on midleg (Scm) is a functional link between PcG repressive complexes in Drosophila
We profiled Sex comb on midleg (Scm), Pc and E(z) in fly embryos and S2 based on BioTAP-XL ChIP-seq. ChIP-seq revealed that Scm is co-localized with PRC1, PRC2, and H3K27me3 in both S2 cells and embryos. Genomic binding/occupancy profiling of Scm, Pc and E(z) by high throughput sequencing
ORGANISM(S): Drosophila melanogaster 
2015-07-09 | E-GEOD-66183 | biostudies-arrayexpress
ProteomicsFly RBPome - Early embryogenesis is characterized by the maternal to zygotic transition (MTZ), in which maternally deposited messenger RNAs are translated and subsequently degraded while zygotic transcription begins
Early embryogenesis is characterized by the maternal to zygotic transition (MTZ), in which maternally deposited messenger RNAs are translated and subsequently degraded while zygotic transcription begins. Posttranscriptional gene regulation by RNA-binding proteins (RBPs) is a dominant force controlli...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2016-04-26 | PXD002992 | Pride
Fly 
Transcriptomicswounded versus nonwounded drosophila embryos
Elucidation of the wound response genes in Drosophila embryos Keywords: response to wounding wild-type drosophila embryos were wounded by laser ablation and compared to unwounded embryos.
ORGANISM(S): Drosophila melanogaster 
2008-04-01 | E-GEOD-10207 | biostudies-arrayexpress
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