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GenomicsRNA seq in sensitive A2780 epithelial ovarian cancer cell with FLYWCH1 knockdown and resistant cells with FLYWCH1 overexpression.
RNA seq in sensitive A2780 epithelial ovarian cancer cell with FLYWCH1 knockdown and resistant cells with FLYWCH1 overexpression.
PRJNA1143573 | ENA
TranscriptomicsRNA seq in sensitive A2780 epithelial ovarian cancer cell with FLYWCH1 knockdown and resistant cells with FLYWCH1 overexpression.
RNAseq in sensitive A2780 cells with shRNA induced knockdown of FLYWCH1 and resistant A2780cis cells with induced overexpression of FLYWCH1.
ORGANISM(S): Homo sapiens 
2025-03-21 | GSE273904 | GEO
UnknownFLYWCH1, a Multi-Functional Zinc Finger Protein Contributes to the DNA Repair Pathway.
Not available
S-EPMC8069811 | biostudies-literature
UnknownIdentification of FLYWCH1 as a regulator of platinum-resistance in epithelial ovarian cancer.
Not available
S-EPMC11970373 | biostudies-literature
UnknownFLYWCH1, a Novel Suppressor of Nuclear β-Catenin, Regulates Migration and Morphology in Colorectal Cancer.
Not available
S-EPMC6277001 | biostudies-literature
UnknownIncreased FLYWCH1 Expression is Negatively Correlated with Wnt/β-catenin Target Gene Expression in Acute Myeloid Leukemia Cells.
Not available
S-EPMC6600431 | biostudies-literature
Proteomics‘Off the shelf’ proximity biotinylation for interaction proteomics
Proximity biotinylation workflows typically require CRISPR-based genetic manipulation of target cells. To overcome this bottleneck, we fused the TurboID proximity biotinylation enzyme to Protein A. Upon target cell permeabilization, the ProtA-Turbo enzyme can be targeted to proteins of interest usin...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-07-12 | PXD025012 | Pride
Flywch1 Proximity labelling Turboid Interactome Protein a 
GenomicsGenome-wide mapping of H3K9me3 in platinum sensitive and resistant epithelial ovarian cancer cell lines.
ChIP-seq for H3K9me3 was performed in A2780 (platinum sensitive) and A2780cis (platinum resistant) cells and in sensitive A2780 cells with shRNA induced knockdown of FLYWCH1.
ORGANISM(S): Homo sapiens 
2025-03-21 | GSE273903 | GEO
UnknownGenetic Complexity of Mitral Valve Prolapse Revealed by Clinical and Genetic Evaluation of a Large Family.
Not available
S-EPMC6676909 | biostudies-literature
GenomicsOff-the-shelf proximity labeling
In this study we developed a new assay to perform proximity biotinylation in cells without the requirement for genetic manipulation or transfection to fuse a biotin ligase to a protein of interest. We show the specificity by targeting H3K9me3 and performing ChIP-seq for the biotin modification. Targ...
ORGANISM(S): Homo sapiens 
2021-07-09 | GSE169317 | GEO
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